ISRCTN22426306已完成不适用
Effect of corticosteroid adjunctive therapy on the clinical course and outcome of severe community-acquired pneumonia (CAP): a randomised, double-blinded study
Institute of Health Carlos III (Instituto de Salud Carlos III) (Spain)0 个研究点目标入组 56 人开始时间: 2005年10月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 56
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Community-acquired pneumonia (CAP) presenting extensive radiographic consolidations (affecting entirely at least two lobes), and respiratory failure (pO2/FiO2 <300).
排除标准
- •Exclusion criteria included:
- •1. Age <18 years and >75 years
- •2. No written informed consent available
- •3. Known hypersensitivity to steroids
- •4. Steroid treatment in the previous 48 hours
- •5. Need of steroid treatment for any reason (asthma, chronic obstructive pulmonary disease [COPD] etc.)
- •6. Uncontrolled diabetes mellitus
- •7. Active peptic ulcer
- •8. Active Mycobacterial or fungal infection
- •9. Reported severe imunosuppresion
- •10. Hospital admission during the previous 8 days
- •11. Empyema
- •12. Extrapulmonary septic manifestations
- •13. Presence of shock
- •14. Need of mechanical ventilation prior to the inclusion into the study
研究者
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