Older Adults' Readiness to Stop Prescribed Medications With Guidance From Health Care Professionals
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- Patient Motivation to Deprescribe
研究概览
简要总结
Polypharmacy, regular use of 5+ prescribed medications, is common among older adults and potentially harmful. Patients differ in their concern about medications, comfort in raising questions about them, and trust and confidence in physician judgment. This pilot observational research will determine older adults' readiness to "deprescribe," that is, stop prescribed medications under physician guidance.
详细描述
The purpose of this research is to assess readiness to deprescribe, that is, to determine how willing patients are to stop prescriptions that may no longer be necessary or may no longer have a favorable benefit-risk ratio. This readiness depends on many factors, including a patient's trust in a health care provider, how proactive patients are in seeking care, and patients' comfort in changing longstanding medical regimens.
The proposed two-wave survey research will use validated instruments and recruit from an older adult research registry to determine (i) readiness to deprescribe at baseline, (ii) correlates of such readiness, and (iii) effects of intercurrent illness and changing health on readiness to deprescribe at 6 months.
Specific aims:
- Determine readiness to deprescribe among a sample of patients with 5+ prescriptions using validated scales.
- Determine correlates of readiness to deprescribe. Patients differing in age, gender, race, education, and comorbidity may differ in willingness to stop prescribed medications.
- Determine the effect of intercurrent illness on readiness to deprescribe. Over 6 months, we anticipate some patients will have a new onset of illness or hospitalization, or increasing levels of disability. We would like to determine if these changes in medical status affect readiness to deprescribe.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •65 years or older
- •Medical visit within past 6 months
- •Self-report of at least 5 regular medications for at least 4 weeks
- •Exclusion criteria:
- •Diagnosis of dementia or score <=4 on Memory Impairment Screen
- •Hospitalization in prior 30 days with change in medications
排除标准
- 未提供
结局指标
主要结局
Patient Motivation to Deprescribe
时间窗: Change over 6 months
Self-report measure (Linsky 2020): range 1-5; high scores = greater readiness to deprescribe; mean (SD) in VA sample 2.99 (0.80)
次要结局
- Self-reported stopping/changing prescription medication(6 months)
研究者
Steven M. Albert
Professor
University of Pittsburgh