Clinical and Laboratory Evaluation of Icon® Resin Infiltration and Vanish™ XT Varnish, on Color Changes of White Spot Lesions

Aim

1. Clinically assess the efficacy of "Icon® resin infiltration" and "VanishTM XT varnish" in restoring the appearance of WSLs
2. Assess patients/parents' satisfaction after "Icon® resin infiltration" and VanishTM XT varnish" application.
3. Evaluate the changes in lesion size by using cross-polarization photography. Materials and Methods The study will be carried out in the "Department of Pediatric Dentistry, Faculty of Dentistry, King Abdulaziz University (KAU)", after approval from the Research Ethics Committee.

Study design A randomized, controlled trial comparing the application of "Icon® resin infiltration" and "VanishTM XT varnish" in parallel groups with a 1:1 allocation ratio. Also, an experimental in vitro study will be conducted.

Clinical trial (Color measurement) Participants, eligibility criteria, and settings A convenient sample of participants attending "King Abdulaziz University Dental Hospital" "KAUDH" will be recruited with WSLs affecting at least one of the labial surfaces of their permanent anterior teeth.

WSLs will be objectively screened Using "DIAGNOdent®" which will quantitively evaluate the loss of the associated fluorescence of WSLs (Q) as well as sound enamel surrounding lesion. The "DIAGNOdent®" device employs blue laser light to illuminate the teeth. The dentin of a tooth comprises fluorophores, which exhibit green fluorescence upon exposure to blue laser light. The presence of a WSL will appear as a dark region surrounded by a green reflective hue, which is observed as a reduction in fluorescence. WSL could easily be overlooked with the absence of "DIAGNOdent®". Only WSLs (Q) scores of 2-9 will be included.