NL-OMON49069尚未招募不适用
The function of CX3CR1 receptors on circulating patrolling monocytes and other leukocytes determine the severity of emphysema in patients with ZZ genotype alpha-1-antitrypsin deficiency - CX3CR1 functionality in patients with alpha-1-antitrypsin deficiency
ongziekten0 个研究点目标入组 56 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 56
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational invasive
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •In order to be eligible for PBMC sampling in this study, a subject must meet
- •all of the following criteria:
- •* Known ZZ-AATD genotype of study patient.
- •* Age between 30 and 75.
- •* Spouses with normal AAT genotype, as determined by a PCR kit:
- •AlphaKit-Quickscreen (see section 6.3, study procedures in study protocol).
- •* Spouses must have normal gas transfer values of the lungs.
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:
- •* ZZ-AATD patient or spouse are current smoker.
- •* Patients or spouses who had any type of infection in the previous 3 months.
- •* Patients or spouses who are treated for any type of cancer.
- •* Any co-morbidity that in the opinion of the investigator may interfere with
- •the interpretation of the primary outcome parameter of the study.
研究者
相似试验
已完成
不适用
ECLAXIR:Search for an Association Between CX3CR1 V249I Polymorphism, Preeclampsia and Endothelial InjuryPreeclampsiaNCT00190177Assistance Publique - Hôpitaux de Paris370
Unknown
不适用
Role of CX3CR1-expressing Cells in Hematologic MalignancyCX3CR1 ProteinDiffuse Large B Cell LymphomaMultiple MyelomaNCT02885623Saint Vincent's Hospital, Korea50
尚未招募
不适用
The clarification of the pathological role of CX3CR1/fractalkine/AIM axis in IgA nephropathyIgA nephropathyJPRN-UMIN000011414Juntendo University, Facility of Medicine15
已完成
4 期
The Effect of Renin Angiotensin System Blockage (RAS) Blockade On PTX3 Levels In Diabetic Patients With ProteinuriaProteinuriaRenin Angiotensin SystemDiabetesNCT00674596Gulhane School of Medicine60
尚未招募
不适用
Role of C-Reactive Protein, Procalcitonin and Serum lactate in detecting of bowel ischemia in patients of bowel obstruction mostly occurring post abdominal surgeryCTRI/2021/08/035353Government Medical College and Hospital Sector Chandigarh