Correlation Between Aqueous Protein Level and Clinical Grading of Flare and Flaremetry.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- compare flaremetry readings with the protein content of the aqueous humor
研究概览
简要总结
The purpose of this study is to compare flaremetry readings with the protein content of the aqueous humor and the clinical grading of flare.
详细描述
A total of 20 patients will be included. 10 patients with uveitis and 10 control patients scheduled for phacoemulsification. Each patient will undego complete ophthalmic examination and clinical biomicroscopic grading of the anterior chamber flare applying the SUN working group grading system. Aqueous specimens will be obtained by anterior chamber paracentesis for protein analysis. Each Patient will undego paracentesis and 0.2 ml of aqueous will be obtained. The aqueous sample will be stored at -70°C until the time of analysis for protein content. Objective assessment of flare will be done.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 10 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •10 patients with uveitis with cataract
- •10 patients without uveitis with cataract
- •Inactive inflammation for at least 3 months
排除标准
- •Infectious uveitis
- •endophthalmitis
- •cases with corneal scar
研究组 & 干预措施
patients with uveitis
Paracentesis of the anterior chamber in Paients with uveitis undergoing cataract surgery
干预措施: Paracentesis of the anterior chamber (Procedure)
patients without uveitis
Paracentesis of the anterior chamber in patients without uveitis undergoing routine cataract surgery
干预措施: Paracentesis of the anterior chamber (Procedure)
结局指标
主要结局
compare flaremetry readings with the protein content of the aqueous humor
时间窗: one month
Compare flaremetry readings with the protein content of the aqueous and the clinical grading.
次要结局
未报告次要终点
研究者
Samir S. Shoughy, MD, FRCS (Glasg.)
Ophthalmologist
The Eye Center and The Eye Foundation for Research in Ophthalmology