Povidone-iodine vs. Chlorhexidine Gluconate - A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 入组人数
- 268
- 试验地点
- 2
- 主要终点
- to determine the rate of wound infection using two standard wound preparations: povidone-iodine and chlorhexidine gluconate
研究概览
简要总结
The purpose of this study is to find out if chlorhexidine gluconate solution is better at reducing the rate of wound infection after cesarean section compared to povidone-iodine.
详细描述
Wound infection is a universal potential morbidity to any type of surgery. Over the years many studies have been completed to evaluate ways to decrease this morbidity. Recent literature has looked at different types of surgical solutions used in pre-operative cleansing. Chlorhexidine and povidone-iodine are two standard surgical prep solutions used on a global scale. The most recent literature has shown that chlorhexidine has a decreased wound infection rate for longer surgeries. Cesarean section, as a surgical time, varies from 20 - 60 minutes. There has been no known literature regarding wound infection rates using these two solutions in elective cesarean sections. This trial will review the rates of wound infection using chlorhexidine and povidone-iodine during elective cesarean section and determine if there is any statistically significant difference between the two solutions. The results could potentially decrease wound infection rates, decrease morbidity, decrease hospital length of stay, and help to guide further surgical management.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age >19 years
- •Gestational age > 37 weeks
- •Booked elective cesarean section
排除标准
- •Gestational age < 37 weeks
- •Premature rupture of membranes
- •Onset of labor prior to procedure
- •Evidence of maternal sepsis; maternal fever > 38.5C
- •LSCS for emergency issues: non-reassuring fetal status, placental abruption, failed induction
结局指标
主要结局
to determine the rate of wound infection using two standard wound preparations: povidone-iodine and chlorhexidine gluconate
时间窗: within 6 weeks following surgery
次要结局
- readmission to hospital(within 6 weeks following surgery)
- extended length of admission(within 6 weeks following surgery)
- need for intravenous antibiotics(within 6 weeks following surgery)
- need for repeat procedure such as drainage(within 6 weeks following surgery)
- increased outpatient surveillance(within 6 weeks following surgery)