Role of MSCT Angiography in Evaluation of Lower Gastrointestinal Bleeding
试验速览
- 阶段
- 不适用
- 入组人数
- 25
- 主要终点
- MSCTA in the evaluation of patients presenting with active lower gastrointestinal bleeding.
研究概览
简要总结
Lower gastrointestinal bleeding occurs distal to the ligament of treitz and may involve the small bowel, colon and rectum .
Active lower gastrointestinal bleeding is a common, potentially life threatening medical presentation that can be challenging to localize and treat .
There are many diseases that may cause lower gastrointestinal bleeding, including angiodysplasia, diverticulosis, benign or malignant bowel neoplasm, inflammatory bowel disease, ischemic bowel disease, and infectious bowel disease.
Often, gastrointestinal bleeding will stop spontaneously, but in approximately 25% of patients, bleeding is massive or recurrent, requiring imaging localization and directed therapy.
详细描述
Accurate and prompt diagnosis of the bleeding source is crucial because mortality can be as high as 40%if there is hemodynamic instability in patients .
Because of the length of GI tract, the multitude of pathologic processes that can result in GI bleeding, imaging plays a primary role in the diagnosis .
Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding .
MSCTA is being increasingly used because it is a widely available, non-invasive and fast diagnostic technique that allows for the visualization of the entire intestinal tract and its lesions, the identification of the vascularity and possible vascular abnormalities. In addition, this technique does not require preparation in patients with acute bleeding.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients presenting to assiut university hospital with active lower gastrointestinal bleeding.
排除标准
- •Patients whom are sensitive to contrast. Pregnant women. Patients with renal insufficiency
研究组 & 干预措施
Patients with GIT bleeding
Patients with active lower Gastrointestinal bleeding
干预措施: Multislice CT Angiography (Device)
结局指标
主要结局
MSCTA in the evaluation of patients presenting with active lower gastrointestinal bleeding.
时间窗: 1 hour
Multislice ct angiography
次要结局
未报告次要终点
研究者
Mina Gergis Naeem
Principal investigator
Assiut University