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临床试验/NCT00506818
NCT00506818已完成不适用

Cognitive and Emotional Impairment After Stroke

Sykehuset Asker og Baerum2 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2007年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
250
试验地点
2
主要终点
Effects of vascular risk-factor-intervention on changes in TMTA, ten-words-test and HAD

研究概览

简要总结

Cognitive and emotional symptoms are often seen in the acute phase of a stroke. The prevalence of such symptoms later and the mechanisms explaining the symptoms are not fully known. The causes of poststroke dementia are likely to be multifactorial (Cerebrovascular Diseases 2006). The investigators want to include all patients with first ever stroke without significant cognitive decline prior to the stroke (IQCODE cut-off 3,7) and follow them up for one year. At baseline we will make stroke classifications, measure neurological deficits according to NIHSS, evaluate cognitive and emotional function and make registrations of vascular risk factors, including precerebral color duplex scan with measurement of IMT in CCA. The investigators will then randomize the patients into multifactorial vascular-risk-factor-intervention in the hospital or care as usual in the primary health care. 8-12 months after stroke onset, survivors will undergo new examinations to evaluate neurological, cognitive and emotional functions, as well as MRI and SPECT.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single

入排标准

性别
All
接受健康志愿者

入选标准

  • First ever stroke or TIA
  • No cognitive decline (IQCODE < 3,7)
  • Survived the acute stroke
  • Expected to live at least for one year after stroke

排除标准

  • Cognitive decline

结局指标

主要结局

Effects of vascular risk-factor-intervention on changes in TMTA, ten-words-test and HAD

时间窗: 8-12 months after stroke onset

次要结局

  • Prevalence of dementia and depression after stroke(8-12 month after stroke onset)

研究者

发起方
Sykehuset Asker og Baerum
申办方类型
Other

研究点 (2)

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