Correspondence of Dietary Intake and Biomarker Data
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 4,878
- 主要终点
- Folate status
研究概览
简要总结
This NHANES analysis compares self-reported dietary folate with serum and red blood cell folate status in U.S. adults.
详细描述
Background: Public health concerns of both low and high folate status exist in the U.S. Recent publications have questioned the utility of self-reported dietary intake data in research and monitoring.
Objective
The purpose of this analysis was to examine the relationship between self-reported folate intakes and folate status biomarkers, and to evaluate their usefulness for several types of applications.
Design: Usual dietary intakes of folate were examined using the National Cancer Institute (NCI) method to adjust 2, 24-hour dietary recalls (including dietary supplements) for within-person variation and compared these intakes with serum and red blood cell (RBC) folate among 4,878 non-pregnant, non-lactating participants ≥19y in NHANES 2011-2012, a nationally representative, cross-sectional survey, with respect to consistency across prevalence estimates and rank order comparisons.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adults, ages 19+ years
排除标准
- •missing data
- •non-pregnant
- •non-lactating
结局指标
主要结局
Folate status
时间窗: Up to 24 months
Comparison of folate in diet and blood
次要结局
未报告次要终点
研究者
Regan Bailey
Nutritional Epidemiologist
National Institute of Health and Nutrition