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临床试验/IRCT20170426033658N2
IRCT20170426033658N2已完成2 期

Comparison of the effect of oral immunotherapy with cow's milk products and conventional desensitization in children with allergy to heated cow's milk: a clinical trial

Vice chancellor for Research of Tehran University of Medical Sciences0 个研究点目标入组 25 人开始时间: 待定最近更新:

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
25

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
2 years 至 15 years(—)
性别
All

入选标准

  • patients two years and older
  • Presentation of skin symptoms such as urticaria, erythema and angioedema
  • gastrointestinal symptoms such as severe vomiting, abdominal pain and diarrhea
  • respiratory symptoms such as rhinitis and bronchospasm
  • Presentation of the symptoms up to two hours after exposure
  • these symptoms should be present at least in last six months
  • positive skin prick test for cow's milk or measurement of sIgE for cow's milk
  • positive challenge test with cow's milk

排除标准

  • cellular immune response that is not mediated by IgE
  • malignancy or severe immunodeficiency disorders
  • using beta blockers
  • uncontrolled severe persistent asthma
  • Cardiovascular disease that epinephrine administration is contraindicated in them
  • Taking immunosuppressive drugs
  • previously diagnosed Eosinophilic Gastrointestinal Disorder in response to milk

研究者

发起方
Vice chancellor for Research of Tehran University of Medical Sciences

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