The Difference Between POSEIDON Group 3 and Group 4 as Regards IVF
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 340
- 试验地点
- 1
- 主要终点
- Clinical pregnancy rates.
研究概览
简要总结
prospective observational study over POSEIDON group 3 and POSEIDON group 4 with antagonist protocol for clinical pregnancy rate outcomes
详细描述
Type of study: prospective observational study.
Study setting: Ain Shams University Maternity Hospital (IVF. unit) Specialized IVF centers in GIZAH
Study period: Until all needed patients have been recruited (about 6 months from start of the study).
Study population: women who attend IVF clinic who will be categorized as poor ovarian responders specifically those categorized as Poseidon group 3 and Poseidon group 4 are planning to undergo ICSI/IVF.
Sampling method: patients will be divided in 2 groups : Group A Poseidon group 3 & Group B Poseidon group 4.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •(Poseidon group 4)
- •Age : ≥ 35 years old
- •AMH : < 1.2
- •Planning for IVF (Poseidon group 3)
- •Age : < 35
- •AMH : < 1.2
- •Planning for IVF
排除标准
- •Chronic medical disorders such as : hypertension, diabetes, etc as it may affect embryo quality and pregnancy rate .
- •Evidence of intrauterine pathology ( polyp , fibroid , adenomyosis) as it affect implantation rate.
- •Evidence uterine congenital anomaly(septum , bicornuate ) as it affects implantation rate.
- •Evidence of hydrosalpinx as it affects implantation rate.
- •Infertility due to azoospermia (male case of infertility) as it affects the rate of fertilization.
- •Patients already on other therapies(DHEA ,steroids, etc) as it affects pregnancy rate.
结局指标
主要结局
Clinical pregnancy rates.
时间窗: Untill all patient has been recruited - about 6 months
number of clinical pregnancy/ number of embryo transfer cycle for each group
次要结局
- Fertilization rate.(Untill all patient has been recruited - about 6 months)
- Implantation rate after embryo transfer(Untill all patient has been recruited - about 6 months)
- Number of high quality grade A embryos on day 3 and blastocyst.(Untill all patient has been recruited - about 6 months)