A pilot safety and acceptability trial of moderated on-line social therapy (MOST) for first-episode psychosis.

Helen Macpherson Smith Trust0 个研究点目标入组 20 人开始时间: 2012年5月14日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•(a) a first episode of a DSM-IV psychotic disorder or mood disorder with psychotic features; (b) aged 15-25 years inclusive; (c) less than or equal to 6 months treatment with an antipsychotic medication prior to registration with the early psychosis service; (d) remission on positive symptoms of psychosis which will be defined as 4 weeks or more of scores of 3 (mild) or below on the subscale items hallucinations, unusual thought disorder, conceptual disorganization, and suspiciousness on the expanded version of the Brief Psychiatric Rating Scale (BPRS). Additional inclusion criteria to ensure low level of risk within MOST include: (e) low aggressiveness which will be defined by a score of 5 or below (with the exception of evidence of threat to others) on the hostility subscale of the expanded version of the BPRS for the month prior to study entry; and, (f) low suicidal risk defined as a score of 4 or below on the suicidality subscale for the month preceding study entry.

•(a) intellectual disability; (b) inability to converse in, or read English; (c) participation in previous CBT or pharmacological trials for psychosis; (d) a DSM-IV diagnosis of either antisocial personality disorder (ASPD) or borderline personality disorder (BPD); (e) pregnancy; (f) medical conditions requiring high level of care; (g) presence of acute psychotic symptoms above a mild level; (h) presence of moderate or above levels of suicidality or hostility.

发起方

Helen Macpherson Smith Trust