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临床试验/NCT06017440
NCT06017440已完成不适用

Effect of Acute Exercise on Sensory and Hedonic Responses to a Fixed Meal in Adolescents With Obesity

University Hospital, Clermont-Ferrand1 个研究点 分布在 1 个国家目标入组 16 人开始时间: 2023年7月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
16
试验地点
1
主要终点
FOOD reward

研究概览

简要总结

While long considered independently, energy expenditure and energy intake have been shown to interact. Fot the last 20 years, the litterature has been describing tyhe effects of an acute bout of exercise on subsequent energy intake and appetitive responses, indicating a potenital anorexigenic effect of intensive exercise in adolescents with obesity. These studies suggest a decrease in hunger, redcued satiety and modified food reward responses.

These results remain however obtained in studies using post exercise ad libitum test meals and this nature of the meal might ahve impact these responses.

The present work tends to assess the effect of acute exercise on subsequent appetite and food reward responses to a fixed meal, in adolescents with obesity.

详细描述

After an inclusion visit to ensure the aptitude of adolescents to complete the entire study, each will have to carry out densitometric measurements (body composition and bone structure). The adolescents will then carry out, in a randomized manner, 2 experimental sessions spaced at least 7 days apart: i) a control session (CON); ii) a session with a pedaling exercise at 65% of their estimated maximum capacity (EX).

During each of these experimental sessions, teenagers will receive a calibrated breakfast at 08:00 am. During the CON session, teenagers should not perform any physical activity during the day and they will be asked to stay at 11 a.m., for 30 minutes, resting in a semi-supine position. During the EX session, teenagers will perform moderate-intensity physical exercise (65% of their estimated maximum capacity) at 11 a.m. At noon, the teenagers will have to consume a calibrated meal. Questionnaires on feelings of hunger will be distributed to them at regular intervals. They will also be asked to complete a 10-minute computer exercise to assess their relationship to food just before and just after the calibrated midday meal (LFPQ. Leeds Food Preference Questionnaire, Liking/Wanting, French version). Sixty minutes after the calibrated meal, teenagers will have an ad libitum buffet available for one hour.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
11 Years 至 16 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Subjects aged 11 to 16 years (inclusive limits), maturation stage 3-5 according to the Tanner classification, with obesity defined by a body mass index (BMI) greater than the 97th percentile according to national curves (Roland- Cachera et al., 1991).
  • Adolescent who has signed the information and consent form and whose holders of parental authority have signed the information and consent form
  • Person subject to a Social Security scheme

排除标准

  • Medical or surgical history deemed by the investigator to be incompatible with the study
  • Presence of diabetes, and any other pathology limiting the application of one or the other strategy to the trial.
  • Taking medications that may interfere with the results of the study
  • Subjects with cardiovascular problems, here we are talking about subjects with a history of cardiovascular and/or neurovascular pathology, as well as subjects presenting cardiovascular and/or neurovascular risk factors (excluding obesity/ overweight).
  • Surgical intervention in the previous 3 months.
  • Subjects undergoing energy restriction or weight loss program through physical activity at the time of inclusion or during the last six months.
  • Consumption of tobacco or alcohol.
  • Special diet.
  • Participation in regular and intense physical and sports activities for more than two hours per week.
  • Teenagers whose parents are under guardianship, curatorship, safeguard of justice or not subject to a social security system
  • Refusal to sign the information and consent notice
  • Person in period of exclusion from another study
  • Pregnant or breastfeeding adolescents on declarative

研究组 & 干预措施

adolescents with obesity

Experimental

There is only one arm as this is an acute randomized study comparing two differents conditions within the same sample of participants.

干预措施: EXERCISE (Behavioral)

adolescents with obesity

Experimental

There is only one arm as this is an acute randomized study comparing two differents conditions within the same sample of participants.

干预措施: CONTROL (Behavioral)

结局指标

主要结局

FOOD reward

时间窗: at lunch time

food reward will be assessed using the leeds food preference questionnaire

Energy intake

时间窗: at lunch time

energy intake will be assessed ad libitum at the following diner

APPETITE FEELINGS

时间窗: immediately after lunch

appetite sensation will be assessed using visual analog scales

次要结局

未报告次要终点

研究者

发起方
University Hospital, Clermont-Ferrand
申办方类型
Other
责任方
Sponsor

研究点 (1)

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