A PATIENT PREFERENCE STUDY OF FROVATRIPTAN VERSUS ZOLMITRIPTAN FOR THE ACUTE TREATMENT OF MIGRAINE - ND

GUIDOTTI0 个研究点开始时间: 2007年6月8日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•consenting ambulant male or non-pregnant female patients between >=18 and <=65 years of age with history of migraine with or without aura according to the IHS criteria, with at least one but not more than six episodes per month during the last 6 months.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•history suggestive of ischaemic heart disease or any atherosclerotic disease indicating an increased risk of coronary ischaemia; ? symptomatic Wolff-Parkinson-White syndrome or cardiac arrhythmias associated with other cardiac accessory conduction pathway disorders; ? history of stroke or transient ischaemic attack (TIA); ? uncontrolled hypertension; ? history of basilar, hemiplegic or ophthalmoplegic migraine; ? severe liver impairment (i.e., Child-Pugh score >=7); ? severe renal impairment (i.e., CrCl <26 ml/min), renal disease, or renal failure; ? known or suspected intolerance of, or hypersensitivity or contraindications to any component of the trial medications, including inert substances (e.g. intolerance to galactose, Lapp?s lactase deficiency, malabsorption of glucose-galactose, phenylketonuria); ? use of either test medication to treat any one of the last three episodes of migraine; ? history of intolerance or inefficacy of at least two triptans for the treatment of migraine attacks; ? current use of propranolol or ergotamine or its derivatives; ? current use or use within the last 2 weeks of MAO-inhibitors; ? abuse of alcohol, analgesics or psychotropic drugs; ? severe concurrent medical condition that may affect the interpretation of clinical trial results; ? pregnancy or breastfeeding; ? participation in a clinical trial, currently or within the previous month; ? inability or refusal to issue the informed consent.

发起方

GUIDOTTI