Effectiveness of Mirror Therapy in Improving Motor Recovery and Hand Function in Patients With Acute Stroke A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 44
- 试验地点
- 2
- 主要终点
- Upper-Limb Function (ARAT total score, 0-57)
研究概览
简要总结
Randomized controlled trial to determine whether mirror therapy (MT), added to conventional physiotherapy, improves upper-limb motor recovery, hand function, spasticity, and range of motion (ROM) in acute stroke compared with conventional physiotherapy alone. Outcomes include ARAT, Motor Assessment Scale, Modified Ashworth Scale, and goniometric ROM.
详细描述
Stroke causes significant upper-limb impairment in the acute stage; early, targeted rehabilitation leverages heightened neuroplasticity. Mirror therapy uses a mid-sagittal mirror to reflect movements of the non-paretic limb, creating the illusion of normal movement in the paretic limb, recruiting mirror neuron circuits and facilitating motor relearning. Prior work suggests MT can improve fine and gross motor skills, reduce spasticity, and increase active ROM. This trial operationalizes a pragmatic MT protocol integrated with standard inpatient/outpatient physiotherapy in acute stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
盲法说明
None (Open Label)
入排标准
- 年龄范围
- 40 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 40-55 years
- •Acute ischemic or hemorrhagic stroke within the last 1 month
- •Unilateral hemiparesis/hemiplegia
- •Medically stable and cleared for rehabilitation
- •Able to follow verbal instructions; MMSE ≥ 24
- •Provides written informed consent
排除标准
- •Recurrent stroke or bilateral involvement
- •Severe cognitive impairment (MMSE < 24)
- •Visual field deficits, unilateral neglect, or severe aphasia interfering with MT
- •Other neurological disorders (e.g., Parkinson's, MS)
- •Orthopedic conditions affecting upper limb/trunk
- •Uncontrolled cardio-respiratory disease limiting exercise
- •Severe spasticity (MAS ≥ 3) in affected limb
- •Concurrent enrollment in other interventional trials
- •Inability/refusal to consent
研究组 & 干预措施
Mirror Therapy + Conventional Physiotherapy
Experimental: Mirror Therapy + Conventional Physiotherapy
Device/Procedure: Mirror Therapy (20 min/session) + immediate Conventional Physiotherapy (20 min/session)
Schedule: 2 sessions/week for 1 week (total: 2 sessions)
MT Procedure: Mirror (box or plain) placed along mid-sagittal plane reflecting the non-paretic limb while hiding the paretic limb. Participants perform bilateral symmetrical movements focusing on the mirror image (e.g., wrist flex/ext, finger flex/ext, elbow flex/ext, reaching & grasping).
Conventional Content (immediately after MT): strengthening & functional task practice (e.g., reaching/transfers), plus targeted hand training: theraputty squeezes, finger extension with rubber band, towel wringing, lifting small objects, reaching overhead/side-to-side with weight, weighted ball toss/catch.
干预措施: Mirror Therapy Conventional Physiotherapy (Behavioral)
Conventional Physiotherapy Only
Procedure: Conventional Physiotherapy (20 min/session), no mirror. Same schedule and exercise menu as above without visual mirror feedback.
Notes: The proposal specifies 1 week duration with 2 sessions/week, 20 min each; centers may extend to clinically standard dosage via protocol amendment if needed.
干预措施: Mirror Therapy Conventional Physiotherapy (Behavioral)
结局指标
主要结局
Upper-Limb Function (ARAT total score, 0-57)
时间窗: 6 Months
Change from baseline to end of week 1; higher scores = better function.
次要结局
- Motor Function (Motor Assessment Scale - relevant upper-limb items, 0-6 per item)(6months)
- Motor Function (Motor Assessment Scale - relevant upper-limb items, 0-6 per item)(6months)