Oral Processing Behavior of Gluten-free and Gluten-containing Breads
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Oral processing behavior
研究概览
简要总结
To attend the increasing demand for gluten-free products, new gluten-free formulations emerged in the market containing alternative ingredients to mimic the protein functionality of wheat. The replacement of wheat, however, has consequences in the sensorial properties of gluten-free products, which can compromise the acceptability of products. This study aims to investigate the oral processing behaviour of gluten-free and gluten-containing breads. Two commercial products, one gluten-free and one gluten-containing bread will be tested either without spread or with butter or mayonnaise. Spreads will be added to the breads to resemble a sandwich consumption which is a more realistic approach than that previously used. The investigators hypothesize that changes in the structure of gluten-free breads resulting from the absence of a strong gluten network can have a prominent impact on the way gluten-free bread is orally processed. The investigators also hypothesize that the addition of spreads will facilitate the oral processing of bread due to an increase in moisture content and lubrication.
The number of chews, number of swallows and eating duration will be determined through video recording of 20 subjects. The texture attributes predominantly at the beginning of mastication and at the swallowing point will be accessed using a check-all-that-apply test. Additionally, the amount of saliva incorporated during chewing will be determined from the spat out food bolus.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 59 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age between 18-59 years old
- •Have good general oral health (self-reported)
- •Have normal smell and taste functions (self-reported)
- •Have a normal body mass index (BMI 18.5-24.9 kg/m2) (based on self-reported weight and height)
- •Have no dental braces or a piercing in or around the mouth (except removable piercings)
- •Have given written informed consent
排除标准
- •Have any food allergy or intolerance for gluten
- •Have mastication and/or swallowing problems caused by neurological problems, i.e. stroke, Parkinson, Alzheimer, Huntington
- •Being pregnant or lactating (self-reported)
- •Use medication that may affect the function of taste, smell, mastication and salivation
结局指标
主要结局
Oral processing behavior
时间窗: Day 1, approximately 30 min
Participants were video recorded during bread consumption and the parameters number of chews, number of swallows and eating duration were extracted from the videos
Texture sensations perceived during chewing
时间窗: Day 2, approximately 30 min
Texture attributes were selected after 5 chewing cycles and at the moment of swallowing using the check-all-that-apply methodology
次要结局
- Saliva content in food bolus(Day 2, approximately 30 min)
研究者
Nicoletta Pelegrini
Associate Professor
University of Udine
