Effect of Laser Acupuncture on Immunological Response and Dyspnea in Post Covid Syndrome Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 主要终点
- change in the level of CD 3 T cells
研究概览
简要总结
Coronavirus (19) is a pandemic that affects many countries allover the world. Many patients experienced symptoms as dyspnea and fatigue after their recovery from coronavirus . These symptoms appear to occur regardless the severity of the infection. In addition, many studies reported change in the inflammatory status and immunity in post covid patients. laser acupuncture is a painless noninvasive modality that is used in treating many diseases. laser acupuncture appear to have a role in relieving symptoms, altering inflammatory status and boosting immunity in post covid patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age will be ranged from 30 to 40 years
- •patients were diagnosed as covid 19 by polymerase chain reaction test using nasopharyngeal swap
- •patients will be negative polymerase chain reaction test (pcr) with symptoms of dyspnea and fatigue.
- •patients will be recruited after 2 weeks post the negative pcr
- •patients who want to participate and complete the study till the end
排除标准
- •patients with photosensitivity
- •pacemaker plantation pregnant women
- •BMI more than 30kg/m2 infection or inflammation at the site of acupuncture laser malignancy uncontrolled diabetes psychiatric disorders or mental retardation
结局指标
主要结局
change in the level of CD 3 T cells
时间窗: after 12 weeks of treatment
5ml of blood will be drawn and serum will be separated. cd3 level will be measured using BD FACS Canto flow cytometer
change in level of interleukin 4
时间窗: after 12 weeks of treatment
BD FACS Canto flow cytometer with BD CBA human th1/th2 cytokine kit will be used
change in level of interleukin 6
时间窗: after 12 weeks of treatment
BD FACS Canto flow cytometer with BD CBA human th1/th2 cytokine kit will be used
change in the level of cd4 T cells
时间窗: after 12 weeks of treatment
cd4 will be measured using BD FACS Canto flow cytometer after blood sample will be separated
change in lymphocyte count
时间窗: after 12 weeks of treatment
BD FACS Canto flow cytometer will be used
change in level of dyspnea
时间窗: after 12 weeks of treatment
mMRC scale is a five point scale to detect degree of dyspnea while performing physical activity. it is ranged from 0-4
次要结局
- change in fatigability(after 12 weeks of treatment)
研究者
Salma Ibrahim Abdelmohsen Alghitany
teacher at faculty of physical therapy, Cairo university
Cairo University