临床试验/NCT00458770

NCT00458770终止不适用

Study of Hypothalamic Metabolism in Spontaneous Cluster Headache Attacks

Assistance Publique Hopitaux De Marseille1 个研究点分布在 1 个国家目标入组 1 人开始时间: 2009年5月1日最近更新: 2014年2月25日

适应症

试验速览

阶段: 不适用
状态: 终止
发起方: Assistance Publique Hopitaux De Marseille
入组人数: 1
试验地点: 1
主要终点: To confirm the existence of a hypothalamic promoter at the origin of Spontaneous Cluster Headache Attacks

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Cluster headache is characterized by unilateral excruciating head pain and autonomic dysfunction. Hypothalamic overactivity was observed in nitrate-induced cluster-headache and in only one case of spontaneous cluster headache 'Sprenger et al, 2004). This prompted the application of hypothalamic deep brain stimulation. The aim of this data is to precise the localisation of the hypothalamic activation.

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Basic Science
盲法: None

入排标准

年龄范围: 18 Years 至 65 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•cluster headache in crisis
•no serious illnesses in progress as cancer, autoimmune disease, liver disease
•patient without chronic psychiatric disease excluding moderate and reactional depression
•no demential disease
•no anxious or depressive disease
•no contraindication to PET scan (pregnancy and breast-feeding)
•social security cover
•written informed consent

排除标准

•No effective contraception taken
•unable to realize a decubitus of 15 minutes long

结局指标

主要结局

To confirm the existence of a hypothalamic promoter at the origin of Spontaneous Cluster Headache Attacks

时间窗: 2 years

次要结局

未报告次要终点

研究者

发起方

Assistance Publique Hopitaux De Marseille

申办方类型

Other

责任方

Sponsor

研究点 (1)

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