Brief Meaning-making Program for Young Adult Cancer Survivors (YACS): An Open-label Randomized Controlled Feasibility Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Fatigue
研究概览
简要总结
The goal of this feasibility study is to learn if a brief meaning-making wellness intervention based on Viktor Frankl's Existential Psychology works to improve fatigue levels in Young Adult Cancer Survivors (YACS) who have completed primary treatment. The main questions it aims to answer are:
- What would be the recruitment and retention rates?
- What might the feedback from participants be?
- Could there be any effects on fatigue and other related symptoms? Researchers will compare meaning-making to usual care (no intervention) to see if meaning-making works to improve fatigue and other symptoms in YACS.
Participants will:
- Complete questionnaires (self-reported outcome measures) at baseline, 1-week post-intervention, and at 1-month follow-up.
- Attend an in-person, two-session brief meaning-making program
详细描述
Background:
Young Adult Cancer Survivors (YACS) refers to young adults aged 18-39 with a history of cancer, with "survivor" status defined as having completed primary treatment for cancer. YACS encompasses both survivors of Adolescent and Young Adult (AYA) cancer (defined as primary cancer onset at age of 15-39) and childhood cancer (defined as primary cancer onset at age of 0-14). According to statistics from the Hong Kong Cancer Registry, there were 1,471 new cases of AYA cancer and 111 cases of childhood cancer in 2023.
Studies have found fatigue to be prevalent and particularly distressing among Young Adult Cancer Survivors (YACS): 1 in every 4 YACS continued to experience persistent chronic fatigue even after a median of 14 years since cancer diagnosis.
In this connection, we propose a brief meaning-making education program, grounded in Viktor Frankl's Existential Psychology, for facilitating fatigue management in post-treatment Young Adult Cancer Survivors.
Methods:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cancer survivors currently aged 18-39, including who are currently either cancer-free, in remission, or receiving maintenance therapy.
- •Having completed primary cancer treatment for at least about 2 months.
- •Able to speak, read, and comprehend Cantonese, and able to comprehend English.
- •Ambulatory
- •No auditory, visual or language or reading disabilities (e.g. aphasia, deafness)
- •Able to complete online questionnaires.
- •Able to use laptop.
- •Willing to accept randomization.
排除标准
- •Current severe or untreated psychiatric disorder that would preclude participation in class activities.
- •Displaying any psychotic symptoms which would hinder class participation.
- •Having physical, sensory disabilities or cognitive impairment that would preclude face-to-face class. attendance and group-based interaction.
- •Unwilling to accept randomization.
- •Currently receiving any type of psychotherapy
- •Having received any Franklian existential psychology-related interventions, Logotherapy or Meaning-centred Psychotherapy before.
- •Remark: Some inclusion and exclusion criteria are purposely omitted at this time to preserve scientific integrity. They will be included after the trial is complete.
研究组 & 干预措施
Control
Subjects randomized to this Control Group will not receive any Intervention.
Meaning-making
Subjects randomized to this experimental arm will receive the Intervention
干预措施: Meaning-making (Other)
结局指标
主要结局
Fatigue
时间窗: Baseline
The Brief Fatigue Inventory (BFI) is used for assessing Fatigue levels. Scores range from 0 to 10, with higher scores indicating greater severity of Fatigue.
Fatigue
时间窗: 1-week Post-intervention
The Brief Fatigue Inventory (BFI) is used for assessing Fatigue levels. Scores range from 0 to 10, with higher scores indicating greater severity of Fatigue.
Fatigue
时间窗: 1-month Follow-up
The Brief Fatigue Inventory (BFI) is used for assessing Fatigue levels. Scores range from 0 to 10, with higher scores indicating greater severity of Fatigue.
次要结局
- Depression(Baseline)
- Depression(1-week Post-intervention)
- Depression(1-month Follow-up)
- Anxiety(Baseline)
- Anxiety(1-week Post-intervention)
- Anxiety(1-month Follow-up)
- Sleep Quality(Baseline)
- Sleep Quality(1-week Post-intervention)
- Sleep Quality(1-week Follow-up)
- Presence of Meaning in Life(Baseline)
- Presence of Meaning in Life(1-week Post-intervention)
- Presence of Meaning in Life(1-month Follow-up)
- Search for Meaning(Baseline)
- Search for Meaning(1-week Post-intervention)
- Search for Meaning(1-month Follow-up)
- Quality of Life, measured by MQOL(Baseline)
- Quality of Life, measured by MQOL(1-week Post-intervention)
- Quality of Life, measured by MQOL(1-month Follow-up)
研究者
Ki Sum Samson WONG
Assistant Lecturer, Li Ka Shing Faculty of Medicine
The University of Hong Kong