The Relationship of Sevoflurane Consumption With Metabolic Age
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 79
- 试验地点
- 1
- 主要终点
- consumption of sevoflurane
研究概览
简要总结
The aim of this clinical study is to determine the consumption of sevoflurane, which is one of the inhalation anesthetics, with metabolic age and basal metabolic rate. The basal metabolic rates and metabolic ages of the patients who will be given sevoflurane- maintained general anesthesia were measured preoperatively. The relationship between the amount of sevoflurane consumption and the measured data of the patients in the postoperative period was examined.
详细描述
Standard monitoring, BIS, TOF (train of four) were performed from the premedication application. Aspect A 2000 (Aspect Medical Systems, Newton) monitor and single-chip BIS electrodes will be used for BIS. The total amount of sevoflurane consumed and MAK values of these components will be recorded. Chronological age, metabolic age, BMR, height, weight, ideal body weight, BMI, body adiposity, body fluid ratio, body fluid care, fat mass, lean body weight, muscle registered, visceral adiposity, obesity degree in the preoperative period of the patients. Values, ASA scores and demographic data will be recorded for the operation process, cutting time, anesthesia time, extubation time, total sevoflurane consumption throughout the case, and the relationship with basal metabolism and metabolic age will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Between the ages of 18-65 who are scheduled for rhinoplasty or septoplasty with ASA I-II Cases lasting 1 to 3 hours
- •Exclude Criteria:
- •Patients at high risk of malignant hyperthermia, with a history of allergy to general anesthesia or any of the drugs to be used in the study, accepted as ASA III- ASA IV
排除标准
- 未提供
研究组 & 干预措施
percent age difference < -6.6%
The percentage age difference in the negative direction represents patients whose metabolic age is greater than their chronological age.
When we analyze the ROC analysis in the negative direction,between Percent Age Difference and Sevoflurane Consumption Amount Calculated According to Metabolic Age, the cut-off value of the percentage age difference is -6,6%.
This group refers to those whose percentage age difference is less than -6.6%
干预措施: Sevoflurane Baxter, 100%, Inhalation Vapour, Liquid 250 mL (Drug)
percent age difference -6.6% to 11.7% those between
When we analyze the ROC analysis in the negative direction,between Percent Age Difference and Sevoflurane Consumption Amount Calculated According to Metabolic Age, the cut-off value of the percentage age difference is -6,6%. When we analyze the ROC analysis in the positive direction, the cut-off value of the percent age difference is 11.7%.
This group refers to those whose percentage age difference between -6.6% and 11.7%
干预措施: Sevoflurane Baxter, 100%, Inhalation Vapour, Liquid 250 mL (Drug)
percent age difference > 11.7%
the percent age difference in the positive direction represents patients whose metabolic age is less than their chronological age.
When we analyze the ROC analysis in the positive direction,between Percent Age Difference and Sevoflurane Consumption Amount Calculated According to Metabolic Age, the cut-off value of the percent age difference is 11.7%.
This group refers to those whose percentage age difference is more than 11.7%
干预措施: Sevoflurane Baxter, 100%, Inhalation Vapour, Liquid 250 mL (Drug)
结局指标
主要结局
consumption of sevoflurane
时间窗: patients during surgery
Reducing patients' consumption of sevoflurane according to metabolic law
次要结局
未报告次要终点
研究者
DUYGU DEMİROZ
associate professor
Inonu University