Temporal Changes in Parasternal Intercostal Muscle Thickening as a Possible Biomarker for Successful Weaning From Mechanical Ventilation: a Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Accuracy of change in PIC-TF in predicting successful weaning from mechanical ventilation
研究概览
简要总结
optimal time to liberate from mechanical ventilation is highly prioritized since improper extubation time lead to serious consequences
详细描述
Several parameters were proposed to assess proper weaning time including diaphragmatic ultrasound and extra-diaghragmatic muscles. previous research concluded an ability of parasternal intercostal (PIC) thickening to predict weaning outcomes. researchers of current study assumed that temporal changes in PIC thickening would provide greater ability to predict weaning outcomes
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Mechanically ventilated for 24 hours or more ready for weaning
排除标准
- •Refusal Tracheostomized Inability to obtain ultrasound views patients with neuromuscular disease
结局指标
主要结局
Accuracy of change in PIC-TF in predicting successful weaning from mechanical ventilation
时间窗: At baseline and 30 minutes after initiation of spontaneous breathing trial
percentage of change in PIC TF in predicting weaning outcome
次要结局
- Accuracy of change in PIC-TF to predict reintubation(At baseline and 30 minutes after initiation of spontaneous breathing trial)
研究者
Mina Adolf Helmy
Lecturer of anesthesia and critical care
Cairo University