NCT03232502Unknown3 期
Pharmacogenetics in Primary Care Psychotropics
适应症
试验速览
- 阶段
- 3 期
- 入组人数
- 130
- 主要终点
- Patient oriented outcome1- Clinical Improvement
研究概览
简要总结
Pragmatic trial of pharmacogenetic testing at the time of prescription for a selective serotonin reuptake inhibitor, tricyclic antidepressant or atypical antipsychotic. Does real time intervention improve patient outcomes?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Prescribed a drug of interest for the first time
排除标准
- •Previous pharmacogenetic testing available
结局指标
主要结局
Patient oriented outcome1- Clinical Improvement
时间窗: 6 months
Clinically significant improvement as noted by physician (Subjective and PHQ-9)
Patient oriented outcome2- Adverse effects
时间窗: 6 months
Number of patients with specific, common side effects (from medical chart)
Patient oriented outcome3- Time to Improvement
时间窗: Up to 6 months
Days to clinical improvement (from medical chart)
Patient oriented outcome5- Visits
时间窗: 6 months
Total number of visits to clinic with medication titration required (from medical chart)
次要结局
未报告次要终点
研究者
相似试验
招募中
不适用
Pharmacist Guided Pre-emptive Pharmacogenetic Testing in Antidepressant TherapyDepressionNCT04507555PD Dr. med. Thorsten Mikoteit190
招募中
不适用
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural ActivationBehavioral ActivationAntidepressant Drug Adverse ReactionObsessive Compulsive Disorder (OCD)Major DepressionAnxiety DisordersMajor Depressive DisorderNCT06763081University of Manitoba160
已完成
不适用
Pharmacogenetic Testing on an Outpatient Population With a Depression DiagnosisMajor Depressive DisorderNCT02443584Avera McKennan Hospital & University Health Center84
已完成
不适用
Pharmacogenetic Testing in an Outpatient Population of Patients With DepressionDepressionNCT02497027Avera McKennan Hospital & University Health Center83
已完成
不适用
Clinical Impact of the Antidepressant Pharmacogenomic Algorithm in an Outpatient Therapy-based Clinical SettingMajor Depressive DisorderNCT02479464Mayo Clinic60