Efficacy of mirtazapine for sleep disturbance and anxiety symptoms compared with selective serotonin reuptake inhibitors in patients with major depressive disorder: a multicenter open-label randomized controlled trial. - Efficacy of mirtazapine for sleep disturbance and anxiety symptoms compared with selective serotonin reuptake inhibitors in patients with major depressive disorder: a multicenter, open-label, randomized, controlled trial.

Department of Psychiatry, Chiba University Graduate School of Medicine0 个研究点目标入组 120 人开始时间: 2010年9月2日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1. Patients without 20-75 years of age at study entry 2. Patients treated to current major depressive episode with the antidepressants as the trial intervention 3. Allergy against mirtazapine, paroxetine, and sertraline 4. Patients treated with pimozide 5. Patients treating with or discontinued within 14 days with selegiline, monoamine oxidase inhibitors 6. Patients with severe hormone diseases 7. Significant risk of suicide (HDRS-17 suicide score 3 or over) 8. Pregnant women or women, who may be pregnant 9. Breast-feeding women 10. Patients with substance abuse/dependence 11. Patients with alcohol abuse/dependence 12. Patients with dementia, bipolar or psychotic disorders, those with a primary diagnosis of obsessive-compulsive disorder or an eating disorder 13. Patient whom examination doctor judge improper as a trial subject

发起方

Department of Psychiatry, Chiba University Graduate School of Medicine