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临床试验/NCT03800732
NCT03800732已完成不适用

The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers: Randomized Cross-over Study.

Federal University of Uberlandia2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2019年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
10
试验地点
2
主要终点
Preprandial metabolic

研究概览

简要总结

This study aimed to verify the influence of night work and food intake during the night shift on the eating behavior of fixed night workers the next day.

详细描述

Night work causes restriction of sleep time and circadian misalignment and, therefore, have been associated with nutritional and metabolic impairments. The objective of the present study is to verify the influence of night work and food intake in this period on the behavior of the following day. The workers selected by criteria and inclusion and exclusion will be evaluated at the baseline: anthropometric parameters, food consumption and perception, duration of food consumption, sleep habits and chronobiological pattern (sleep monitoring by actigraphy, chronotype, social jet lag), parameters biochemical (blood count, lipidogram, C-reactive protein, cortisol, glucose, insulin).Subsequently, 30 workers will integrate a randomized and controlled crossover clinical study with three randomly established interventions: (1) two nights of work without meals during the shift; (2) two nights of work with a meal during the shift; (3) two nights sleep. Participants will go to the laboratory the morning after the second night of each condition to offer a test meal ad libitum, which will consist of foods of various compositions and food groups. Preprandial metabolic assessments will be conducted (ghrelin, GLP-1 - glucagon-like peptide 1, PYY-peptide YY). The following postprandial evaluations will be carried out and in the 24 hours following the experiment: food choices (record of all foods) and food perceptions (hunger, appetite, satiety and eating). It is expected to determine how nocturnal versus nocturnal work, and nocturnal fasting versus nocturnal fasting affect the next day's food choices.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
20 Years 至 50 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Agree to participate in the study and sign the Informed Consent Form (EHIC).
  • No significant changes in body mass in the last 6 months.
  • With stable food and sleep routine in the last two months.

排除标准

  • Failure to provide the information or material necessary for the development of the study.
  • Report of chronic non-communicable diseases.
  • Report of diagnosed and untreated psychiatric disorders.

结局指标

主要结局

Preprandial metabolic

时间窗: 6 months

Ghrelin, GLP-1 - glucagon-like peptide 1, PYY-peptide YY

Change of food perceptions

时间窗: 6 months

To evaluate appetite, satiety and postprandial satisfaction, a visual analogue scale was applied before and after consumption of the proposed meal, with the questions, "How much hunger did you have before the meal?"; "After the meal, how did you feel?"; "How much did you like the meal?", Signaling all responses on a 0 to 10 cm scale.

次要结局

  • Food behavior(6 months)

研究者

发起方
Federal University of Uberlandia
申办方类型
Other
责任方
Principal Investigator
主要研究者

Cibele Aparecida Crispim

Principal investigator

Federal University of Uberlandia

研究点 (2)

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