NCT02076087已完成不适用
Immune Characterization of Subcutaneous Adipose Tissue
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- Determine the types of immune cells and the relative prevalence of each type and sub-type, in subcutaneous adipose tissue of normal weight, overweight, obese and lipedema adults.
研究概览
简要总结
The overall goal of this proposal is to characterize the immune cell profile of subcutaneous abdominal adipose tissue in lean, overweight, obese and lipedema adults, and to evaluate potential associations between different adipose tissue immune cell types and metabolic profile.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women of all races and ethnicity
- •Age between 18 and 65 years
- •Body Mass Index (BMI) ≥ 18.5 kg/m²
- •Weight stable (+/- 3% during the last 2 months before enrollment)
- •Women already scheduled for above mentioned procedures
排除标准
- •Diabetes Mellitus
- •Recent (<5 years) history of cancer (except in situ ductal breast carcinoma)
- •Chemotherapy and/or radiation therapy within 4 months before enrollment
- •Immune system diseases (i.e., autoimmune disorders, acquired immunodeficiency syndrome)
- •Pregnant or breastfeeding
- •Take any medication that might affect immune function
- •Severe organ dysfunction
- •BMI <18.5 kg/m² or size of each breast is >600 grams, if scheduled for bilateral breast reconstruction
结局指标
主要结局
Determine the types of immune cells and the relative prevalence of each type and sub-type, in subcutaneous adipose tissue of normal weight, overweight, obese and lipedema adults.
时间窗: intraoperative
次要结局
- Determine the relationships among specific types and subtypes of immune cells, adiposity and cardiometabolic risk.(Baseline)
研究者
研究点 (1)
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