NCT00853476已完成不适用
The Standard Concentration of Morphine as a Positive Control for Intradermal Skin Test
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Wheal diameter from morphine skin test at different concentrations compared to standard histamine between 15-30 minutes after skin test
研究概览
简要总结
This study aims to compare skin reactivity results between morphine and histamine as a positive control agents in intradermal skin test.
详细描述
Histamine hydrochloride and different concentrations of morphine sulfate will be intradermally injected and wheal diameter size will be comparatively measured between 15-30 minutes' time points after the test.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18-60 years old
排除标准
- •immunodeficiency state
- •severe skin diseases
- •severe medical illnesses
- •malnutrition
- •uncontrolled asthma
- •pregnancy
- •received oral or systemic corticosteroid within 1 month before this study
- •receiving immunosuppressive agents
- •taken antihistamine within 3 days before this study
- •taking beta-blocker
- •previous history of immunotherapy
- •have hypersensitivity reaction to morphine/opiates
结局指标
主要结局
Wheal diameter from morphine skin test at different concentrations compared to standard histamine between 15-30 minutes after skin test
时间窗: 30 minutes
次要结局
- Side effects(24 hours)
研究者
研究点 (1)
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