Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Isala
- 入组人数
- 145
- 试验地点
- 1
- 主要终点
- Postoperative pain after removal of third molar
研究概览
简要总结
This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal
In this prospective, randomized controlled trial,130 patients who underwent mandibular third molar surgical removal were divided into two groups: one group used chlorhexidine for postoperative rinsing and the other did not rinse. Pain levels, measured using the Numeric Rating Scale (NRS), were recorded daily for the first seven days post-surgery. Paired-samples t-tests were utilized for data analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adults (18+) referred by their dentist for third molar removal
排除标准
- •active pericoronitis or other infections
- •planned coronectomy
- •chronic pain
- •pregnancy
- •known allergies to local anesthesia
研究组 & 干预措施
No post-operative rinsing
Those allocated to the control group received no post-operative rinsing
Post-operative rinsing with chlorhexidine
In the rinsing group, the patients received a bottle of 0,2% chlorhexidine
干预措施: Chlorhexidine Digluconate Mouthwash without Alcohol (Other)
结局指标
主要结局
Postoperative pain after removal of third molar
时间窗: 7 days after the inclusion pain was measured on a numerical rating scale
The primary endpoint is the difference in the postoperative pain measured on a numerical rating scale (NRS) evaluated at seven days
次要结局
- Post-operative complications(7 days after the treatment the patient was seen at the outpatient clinic for clinical assessment. At this moment the number of patients with alveolitis, foodimpaction and bleeding was scored.)
研究者
Jeroen van der Sleen
Oral Surgeon and Principal Investigator
Isala