NCT00330889已完成不适用
A Study of the Pharmacodynamic Effects of Prednisolone on Whole Blood Protein and Gene Expression in Rheumatoid Arthritis Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Modified Disease Activity Score (DAS28), which was composed of swollen and tender joint counts at 28 sites, a patient's global assessment of disease activity using a visual analogue scale (VAS), and ESR.
研究概览
简要总结
This study will assess the Pharmacokinetic (PK) and Pharmacodynamic (PD) effects of Prednisolone on Rheumatoid Arthritis (RA) patients.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Modified Disease Activity Score (DAS28), which was composed of swollen and tender joint counts at 28 sites, a patient's global assessment of disease activity using a visual analogue scale (VAS), and ESR.
时间窗: 14 days
The levels of selected markers of inflammation, which could include (but were not limited to) ESR, C-reactive protein (CRP), interleukin-6 (IL-6), Rheumatoid factor (RF), and soluble tumor necrosis factor-receptor (TNF-R)
时间窗: 14 days
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
1 期
A Study to Assess the Pharmacodynamics (PD) of Prednisoline in Healthy Male SubjectImmunoscienceNCT03196557Bristol-Myers Squibb24
进行中（未招募）
1 期
A Study of the Pharmacodynamic Effects of Prednisolone on Whole Blood Protein and Gene Expression in Rheumatoid Arthritis PatientsRheumatoid arthritisEUCTR2005-000902-30-GBGlaxoSmithKline Research & Development Limited
招募中
2 期
Effect of Prednisolone on treatment of COVID-19COVID-19 disease.COVID-19U07.2, U07IRCT20081027001411N3Tehran University of Medical Sciences60
尚未招募
1 期
Investigating the effect of prednisolone in the bronchoscopic procedure in the treatment of patients with tracheal stenosisTracheal stenosis.IRCT20230410057872N1Ghoum University of Medical Sciences40
已完成
不适用
Pharmacokinetic Interactions With Prednisolone in Healthy Volunteers and HIV-infected Patients Receiving Single-Dose PrednisoneHealthyNCT00072644National Institutes of Health Clinical Center (CC)75