The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
研究概览
简要总结
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
详细描述
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 10 Years 至 50 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Allergic rhinitis patients age 10-50 years old
- •Control: healthy volunteer age 18-50 years old
排除标准
- •Chronic illness such as cardiovascular diseases, liver diseases
- •History of anaphylaxis
- •Pregnancy
研究者
Punchama Pacharn
Principal investigator
Mahidol University