NCT00788905Unknown不适用
Uremic Toxin Removal, Blood Cell Kinetics, and Inflammatory Response in Patients Treated With the Allient System
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 3
- 主要终点
- Clearance of specific waste products from blood determined through subject blood and dialysate samples
研究概览
简要总结
The purpose of the study to determine whether the level of inflammation may be decreased, the lifespan of red blood cells increased and the clearance of waste products in the blood improved through the use of the Allient System as compared to conventional hemodialysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Maintenance in-center hemodialysis
- •Age greater than or equal to 18 years
- •Has been on hemodialysis for at least 4 months
- •Uses a standard single-pass dialysis machine with a high-flux dialyzer
排除标准
- •Hospitalization during the 8 weeks preceding enrollment
- •Infection requiring antibiotic treatment during the 8 weeks preceding enrollment
- •Central venous cather as dialysis access
- •Uncontrollable blood coagulation anomalies
- •Dialysis regimen other than 3 times weekly
- •In ability to understand the English language and give informed consent for participation in the study
结局指标
主要结局
Clearance of specific waste products from blood determined through subject blood and dialysate samples
时间窗: 3 weeks
次要结局
- Inflammation as determined by levels of specific inflammatory markers(3 weeks)
- Red blood cell lifespan determined through a measurement of CO in the subject's breath(3 weeks)
研究者
研究点 (3)
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