The Impact of FoodforCare at Home on Quality of Life of Cancer Patients Undergoing Chemotherapy.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 148
- 试验地点
- 2
- 主要终点
- Quality of life and overall health status
研究概览
简要总结
Cancer patients receiving treatment such as chemotherapy experience a variety of symptoms that interfere with their appetite and their ability to eat and enjoy meals. Therefore, adapting meals in a way that responds to these symptoms might be a good strategy to improve patient satisfaction, nutritional status and hence, quality of life. In this vein, the investigators hypothesize that meals from FoodforCare at Home will contribute to the quality of life of cancer patients undergoing chemotherapy when compared to usual care.
详细描述
Cancer patients receiving treatment such as chemotherapy experience a variety of symptoms that interfere with their appetite and their ability to eat and enjoy meals. Several studies suggest that nutritional intake increases when the patient is satisfied about the quality of the meals. Therefore, adapting meals in a way that responds to these symptoms might be a good strategy to improve patient satisfaction, nutritional status and hence, quality of life. In this vein, the investigators hypothesize that meals from FoodforCare at Home will contribute to the quality of life of cancer patients undergoing chemotherapy when compared to usual care. Also, the investigators expect that this strategy will have a positive effect on patient satisfaction, other nutrition-related issues, including nausea and vomiting, on nutritional intake per se and hence, on the nutritional status. Additional benefits might include reduced use of medication, especially anti-emetics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18 years or older
- •diagnosed with cancer
- •receiving chemotherapy according to a minimum schedule of every 2 weeks
- •living within a 40 km radius around the Radboud University Nijmegen Medical Centre
- •written informed consent
排除标准
- •renal insufficiency (MDRD-GFR (glomerular filtration rate) < 60ml/min and/or proteinuria)*
- •dementia or any other condition which makes it impossible to fill out questionnaires correctly
- •unable to understand or speak Dutch
- •depending on artificial nutrition in the form of Oral Nutritional Supplements, tube feeding or total parenteral nutrition
- •swallowing or passage problems
- •proteinuria is defined in case of a protein creatinine ratio > 0.5g/10mmol or an albuminuria > 300mg/day. This is checked by default before the start of chemotherapy by the treating physician to decide whether or not the patient is eligible for receiving chemotherapy.
结局指标
主要结局
Quality of life and overall health status
时间窗: 3.5 months
EORTC-Quality of Life-C30 questionnaire filled in before chemotherapy, two times during chemotherapy and after chemotherapy. This questionnaire consists of 30 questions and a total score ranging from 0-100 is calculated based on these questions. The higher the score, the higher the quality of life of the patient.
次要结局
- Nutritional intake(3.5 months)
- Muscle strength(3.5 months)
- Nutritional status(3.5 months)
- Functional score(3.5 months)
- Quality of life caregiver(3.5 months)
- Medication use(3 weeks)
- Symptoms(3 weeks)
- Patient satisfaction(1 day)
- Functional status(3.5 months)