Evaluation of the effectiveness of toothpastes in reducing gum bleeding

Faculdade de Odontologia da Universidade de São Paulo0 个研究点开始时间: 2019年9月23日最近更新: 2023年5月29日

适应症

试验速览

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•Good general health; ability to read, understand and sign the Informed Consent Form; willingness to comply with study procedures and sampling schedules; at least 20 natural permanent teeth without crown (excluding third molars); mean gingival index (Löe & Silness 1967) greater than or equal to 1.5; at least 6 teeth with a minimum of one bleed site on marginal probing

•Have a history of allergy to previously used oral hygiene products or their ingredients; have a history of alcohol or drug abuse; have infectious diseases (e.g hepatitis or AIDS); have a medical condition that could compromise patient safety or the quality of study results; need antibiotics before dental treatment; use anti-inflammatory, immunosuppressive, antimicrobial, anticoagulant or antibiotic drugs within 30 days prior to the start of the study; continuous use of medications known to affect gum tissues; have important oral conditions (including but not limited to oral or soft tissue hard tumor (s), gingival hyperplasia, moderate to severe periodontitis including two or more periodontal pockets greater than 5 mm with bleeding on probing),presence of orthodontic bands or removable partial dentures; presence of five or more carious lesions requiring immediate restorative treatment; being pregnant or breastfeeding; referring to the use of tobacco products; having any pre-existing medical condition prohibiting the subject from eating or drinking for periods of up to 2 hours, have participated in a clinical study involving oral care products in the previous month.

发起方

Faculdade de Odontologia da Universidade de São Paulo