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临床试验/NCT05517941
NCT05517941已完成不适用

Effect of Active Cycle Breathing Technique Along With Incentive Spirometer on COVID19 Patient

Cairo University2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年9月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
2
主要终点
arterial blood gas

研究概览

简要总结

this study will be conducted to investigate the effect of Active Cycle Breathing Technique and incentive spirometer on COVID19 patient

详细描述

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new coronavirus that emerged in 2019 and causes coronavirus disease 2019 (COVID-19).Individuals with COVID-19 can present with an influenza-like illness and respiratory tract infection demonstrating fever (89%),cough (68%), fatigue (38%), sputum production (34%) and/or shortness of breath (19%). The spectrum of disease severity ranges from asymptomatic infection or mild upper respiratory tract illness through to severe viral pneumonia with respiratory failure and/or death. Current reports estimate that 80% of cases are asymptomatic or mild; 15% of cases are severe (infection requiring oxygen); and 5% are critical, requiring ventilation and life support. Based on emerging data, individuals at the highest risk of developing severe COVID-19 disease requiring hospitalization and/or ICU support are those who are older, male, have at least one co-existing comorbidity, elevated D-dimer levels, and/or lymphocytopenia. Active cycle breathing techniques (ACBT) is a cycle of techniques consisting of breathing control, lower thoracic expansion exercises and the forced expiration technique modifiable to individual patients. It assists bronchial clearance by enhancing mucociliary clearance whilst reducing adverse effects such as hypoxemia or increased airflow obstruction. Incentive spirometry (IS) is a type of deep breathing exercise that is widely used for lung expansion and the prevention of pulmonary complications in children, adults, and the elderly. IS is used to encourage the patient to inhale to lung capacity through maximal inspiration aided with visual feedback. These maneuvers increase transpulmonary pressure and therefore increase chest-wall volume.one hundred patients will be allocated randomly to two groups; one group will receive active cycle breathing with an incentive spirometer and the other will receive active cycle breathing

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

盲法说明

random generator

入排标准

年龄范围
45 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ages from 45-75 years old
  • COVID-19 patients with SpO2 > 85
  • oxygen face Mask or a reservoir mask

排除标准

  • Mechanically ventilated,
  • Chronic respiratory disease (defined as asthma or chronic obstructive pulmonary disease),
  • End-stage renal disease,
  • Liver disease (defined as compensated/decompensated liver cirrhosis),
  • Chronic neurological disease (defined as previous neurological disease),
  • Chronic cardiovascular disease,
  • Active smoker

结局指标

主要结局

arterial blood gas

时间窗: up to two weeks

arterial blood gas analysis will be measured using arterial blood sample

次要结局

  • Oxygen saturation(up to two weeks)
  • C-reactive protein(up to two weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Al Shaymaa Shaaban Abd El Azeim

principle investigator. alshaymaa shaaban abd el-azeim

Cairo University

研究点 (2)

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