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临床试验/NCT05181319
NCT05181319Unknown不适用

Development of a Nomogram for Predicting Bronchopulmonary Dysplasia in Infants

Kai Mu1 个研究点 分布在 1 个国家目标入组 5,000 人开始时间: 2018年1月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
5,000
试验地点
1
主要终点
bronchopulmonary dysplasia occurs

研究概览

简要总结

In this Multi-center study performed from January 2018, we reviewed data on infants whose gestational ages were below 36 weeks. we collected data containing maternal diseases and neonatal clinical features. LASSO regression was used to select variables for the risk model. Then, we used multivariable logistic regression to build the prediction model incorporating these selected features. Discrimination was assessed by the C-index, and and calibration of the model was assessed by and calibration curve and the Hosmer-Lemeshow test.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
— 至 1 Day(Child)
性别
All
接受健康志愿者

入选标准

  • Patients were recruited from Multi-center Collaborative Group Hospital Neonatal Intensive Care Unit (NICU) Department.
  • Patients with gestational age <36 weeks
  • admitted to the NICU within 24 h after birth
  • the length of stay was more than 1 week

排除标准

  • patients with inherited disease, metabolic disorders and multiple malformations.

结局指标

主要结局

bronchopulmonary dysplasia occurs

时间窗: 2 weeks after admission

Number of cases of bronchopulmonary dysplasia

次要结局

未报告次要终点

研究者

发起方
Kai Mu
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Kai Mu

professor

Qianfoshan Hospital

研究点 (1)

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