跳至主要内容
临床试验/NCT04880057
NCT04880057Unknown不适用

Effects of Agility Training on Executive Function, Dual Task Performance and Brain Activation in Healthy Adults

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2021年8月2日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
70
试验地点
1
主要终点
Executive function- N-back task (3-back)

研究概览

简要总结

This study will investigate the effect of agility training on executive function, dual task walking and brain activation in healthy adults. Participants (N=70) will be randomly assigned to resistance+aerobic training group (RAeT) or agility training group (AT). Participants in RAeT (n=35) will receive 15-minute lower extremity workout first and then 25-minute moderate intensity (60-75% predicted maximal heart rate) aerobic training. Participants in AT (n=35) will do the agility exercise program consisting of technical drills, pattern running and reactive agility training. The intervention will be twelve-time group intervention (3-5persons) in four weeks, 50 minutes per session (5-minute warmup, 40- minute main training, 5-minute cool-down). Participants will undergo three measurement time points (pre-, post-intervention and one month follow-up). Outcome measures will include executive function (N-back test, stroop test and Wisconsin card sort test), single and dual task walking performance and brain activity (fNIRS on prefrontal cortex, supplementary motor area and premotor cortex). Two-way analysis of variance (ANOVA) with Tukey post-hoc test will be used to examine the group x time interaction on three outcome measures.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
20 Years 至 30 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •(1) age between 20 to 30 years, and (2) ability to walk 20 meters independently without an assistive device.

排除标准

  • •(1) overweight (BMI>24), (2) any smoker or alcohol abusers, (3) suffering from chronic diseases that loss of control, (4) Unstable physiological conditions, such as abnormal signs like high blood pressure, headache, dyspnea, fever, etc., (5) any neuromuscular or cardiopulmonary diseases that would influent the exercise performance, and (6) suffering from diseases which exercises are their contraindications

研究组 & 干预措施

Resistance+Aerobic training group

Active Comparator

Resistance+Aerobic training group (RAeT) RAeT includes resistance training (RT) program and aerobic training (AeT) program.

干预措施: Resistance+Aerobic training (Other)

Agility training group

Experimental

Agility training

干预措施: Agility training (Other)

结局指标

主要结局

Executive function- N-back task (3-back)

时间窗: Change from Baseline score at 7 weeks

N-back task (3-back) is used to measure working memory

Single walking performance- Cadence

时间窗: Change from Baseline cadence at 7 weeks

The unit is steps per minutes

Single walking performance- Stride length

时间窗: Change from Baseline cadence at 7 weeks

The unit is cm

Dual task walking performance- Cadence

时间窗: Change from Baseline cadence at 7 weeks

The unit is steps per minutes

Dual task walking performance- the correct rates of arithmetic task

时间窗: Change from Baseline cadence at 7 weeks

The participants will be instructed to subtract by 7 serially from a 3-digit number while walking at their fastest speed in dual task walking condition

Executive function- Stroop test

时间窗: Change from Baseline score at 7 weeks

Stroop test is used to measure the selective attention and conflict resolution.

Single walking performance- Walking speed

时间窗: Change from Baseline cadence at 7 weeks

The unit is length (cm) per seconds

Dual task walking performance- Stride length

时间窗: Change from Baseline cadence at 7 weeks

The unit is cm

Dual task walking performance- Step duration

时间窗: Change from Baseline cadence at 7 weeks

The unit is seconds

Executive function- Wisconsin card sort test

时间窗: Change from Baseline score at 7 weeks

Wisconsin card sort test is an easy way to assess the ability of mental set shifting.

Single walking performance- Step duration

时间窗: Change from Baseline cadence at 7 weeks

The unit is seconds

Dual task walking performance- Walking speed

时间窗: Change from Baseline cadence at 7 weeks

The unit is length (cm) per seconds

Single walking performance- Walking speed

时间窗: Change from Baseline cadence at 3 weeks

The unit is length (cm) per seconds

Executive function- N-back task (3-back)

时间窗: Change from Baseline score at 3 weeks

N-back task (3-back) is used to measure working memory

Executive function- Stroop test

时间窗: Change from Baseline score at 3 weeks

Stroop test is used to measure the selective attention and conflict resolution.

Executive function- Wisconsin card sort test

时间窗: Change from Baseline score at 3 weeks

Wisconsin card sort test is an easy way to assess the ability of mental set shifting.

Single walking performance- Cadence

时间窗: Change from Baseline cadence at 3 weeks

The unit is steps per minutes

Single walking performance- Stride length

时间窗: Change from Baseline cadence at 3 weeks

The unit is cm

Single walking performance- Step duration

时间窗: Change from Baseline cadence at 3 weeks

The unit is seconds

Dual task walking performance- Walking speed

时间窗: Change from Baseline cadence at 3 weeks

The unit is length (cm) per seconds

Dual task walking performance- Cadence

时间窗: Change from Baseline cadence at 3 weeks

The unit is steps per minutes

Dual task walking performance- Stride length

时间窗: Change from Baseline cadence at 3 weeks

The unit is cm

Dual task walking performance- Step duration

时间窗: Change from Baseline cadence at 3 weeks

The unit is seconds

Dual task walking performance- the correct rates of arithmetic task

时间窗: Change from Baseline cadence at 3 weeks

The participants will be instructed to subtract by 7 serially from a 3-digit number while walking at their fastest speed in dual task walking condition

次要结局

  • Brain activities over supplementary motor area- Single walking(Change from Baseline at 7 weeks)
  • Brain activities over premotor cortex- Dual task walking(Change from Baseline at 7 weeks)
  • Brain activities over premotor cortex- Executive function(Change from Baseline at 7 weeks)
  • Brain activities over supplementary motor area- Dual task walking(Change from Baseline at 7 weeks)
  • Brain activities over supplementary motor area- Executive function(Change from Baseline at 7 weeks)
  • Brain activities over primary motor cortex - Single walking(Change from Baseline at 7 weeks)
  • Brain activities over primary motor cortex - Dual task walking(Change from Baseline at 7 weeks)
  • Brain activities over primary motor cortex- Executive function(Change from Baseline at 7 weeks)
  • Brain activities over premotor cortex- Single walking(Change from Baseline at 7 weeks)
  • Brain activities over premotor cortex- Executive function(Change from Baseline at 3 weeks)
  • Brain activities over supplementary motor area- Executive function(Change from Baseline at 3 weeks)
  • Brain activities over primary motor cortex- Executive function(Change from Baseline at 3 weeks)
  • Brain activities over premotor cortex- Single walking(Change from Baseline at 3 weeks)
  • Brain activities over supplementary motor area- Single walking(Change from Baseline at 3 weeks)
  • Brain activities over primary motor cortex - Single walking(Change from Baseline at 3 weeks)
  • Brain activities over premotor cortex- Dual task walking(Change from Baseline at 3 weeks)
  • Brain activities over supplementary motor area- Dual task walking(Change from Baseline at 3 weeks)
  • Brain activities over primary motor cortex - Dual task walking(Change from Baseline at 3 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

Agility Training on Executive Function, Dual Task... | 临床试验