ultrasound guided preoperative Inferior Vena Cava, subclavian vein collapsibility and aorta canal index for prediction of hypotension in geriatric patients undergoing orthopaedic surgery under central neuraxial block
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- to evaluate the predictive value of three ultrasound parameters collapsibility of Inferior vena cava, collapsibility of subclavian vein and aorta canal index for prediction of hypotension in elderly patients undergoing orthopaedic surgeries under central neuraxial block
研究概览
简要总结
Central neuraxial block is the oldest and most commonly used anaesthetic technique for lower limb orthopaedic surgeries . While there are certain advantages to regional anaesthesia like it provides adequate analgesia and muscle relaxation , it can be easily administered and the mental functions of the patient do not get altered , patients can be mobilized and discharged earlier and there are lower chances of deep vein thrombosis , it ensures better postoperative pain management lesser chances of nausea vomiting , less need of polypharmacy. Hypotension after administration of spinal anaesthesia is due to vasodilation causing a decrease in systemic vascular resistance and cardiac output which occurs due to blockade of pre ganglionic sympathetic fibres or when the spinal anesthesia reaches T4 to T6 level causing a decrease in systemic vascular resistance (SVR) by 23-26% , left ventricular end diastolic volume by 20 %, central venous pressure by 2-3 mmhg. In addition, as the age advances, the risk of hypotension after central neuraxial block increases significantly . This could be due to higher degree of resting sympathetic tone which explains the greater decrease in SVR after sympathetic blockade when compared to younger patients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 60.00 Year(s) 至 85.00 Year(s)(—)
- 性别
- All
入选标准
- •Orthopaedic surgery under central neuraxial block age more than 60 years ASA I II and III.
排除标准
- •patients refusal age less than 60 years asa more than III BMI more than 30kg per meter square absolute or relative contraindication to Spinal anaesthesia patients with tachycardia atrial fibrillation left bundle branch block on egg patients with pulmonary hypertension patients with mitral/ pulmonary valve regurgitation grade 3 or 4 severe aortic stenosis patients with peripheral vascular disease patients with respiratory distress patients with implantable pacemaker patients with mental ioncompetence emergency surgery.
结局指标
主要结局
to evaluate the predictive value of three ultrasound parameters collapsibility of Inferior vena cava, collapsibility of subclavian vein and aorta canal index for prediction of hypotension in elderly patients undergoing orthopaedic surgeries under central neuraxial block
时间窗: Intra operative period
次要结局
- to compare predictive values of these three ultrasonographic methods to detect hypotension in elderly patients undergoing orthopaedic surgery under regional anaesthesia & to determine which parameter is the most accurate indicator of hypotension after central neuraxial block(Intraoperative period)
- to assess incidence of hypotension in elderly patients undergoing orthopaedic surgery under regional anesthesia(Intra operative period)
- to evaluate vasopressor requirement in patients during intraoperative management(Intraoperative period)
