Evaluation of Autogenous Dentin Graft Versus Demineralized Freeze-Dried Bone Allograft in the Treatment of Class ΙΙ and ΙΙΙ Mandibular Furcation Defects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Probing pocket depth
研究概览
简要总结
Randomized clinical and radiographic trial
详细描述
Evaluation of Autogenous Dentin Graft versus Demineralized Freeze-Dried Bone Allograft in the Treatment of Class ΙΙ and ΙΙΙ Mandibular Furcation Defects
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Presence of class II and/or ΙΙΙ furcation defects in mandibular first or second molars according to criteria outlined by Hamp et. al.
- •Horizontal probing depth ≥3 mm using Naber's probe.
- •Clinical attachment level ≥3 mm measured from cemento-enamel junction (CEJ) till the deepest probing depth.
- •Evidence of radiolucency in the furcation area on panoramic radiograph.
- •Patients who will be assigned for groups (I and II) should present with teeth required for extraction due to advanced periodontal bone loss or other indications such as hopeless wisdom teeth or orthodontic indications or unrestorable fractured teeth as a source for autogenous dentin graft (ADG).
排除标准
- •Medically compromised patients and systemic conditions precluding periodontal surgery.
- •Mandibular first or second molars with root caries or endodontic treatment.
- •Smokers, diabetics, pregnant or lactating women.
- •History of chemotherapy, radiotherapy in head and/or neck region.
- •Bisphosphonate therapy.
结局指标
主要结局
Probing pocket depth
时间窗: Measured at baseline, 6 months and 12 months
According to Ramfjord, clinical parameter measured by UNC periodontal probe from a fixed point to the deepest probing depth. Using stent to standardize the measurements.
Clinical attachment level
时间窗: Measured at baseline, 6 months and 12 months
According to Ramfjord, clinical parameter measured by a Naber\'s probe. Using stent to standard measurements.
Bleeding on probing
时间窗: Measured at baseline, 6 months and 12 months
According to Ramfjord, the bleeding at each site observed after probing and recorded positive if bleeding was observed within 30 seconds, if not was recorded as negative.
次要结局
- Radiographic outcome(measured at baseline and 1 year follow up)
研究者
Banan Lotfy Mohamed Amer
Assistant lecturer at periodontology department, Principal Investigator, MSC
Tanta University