A Randomized Controlled Trial Comparing the Effects of Thoracic Mobilization and Conventional Respiratory Therapy on Cough Capacity, Dyspnea, and Pulmonary Function in Patients With Restrictive Lung Disease
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Pulmonary function test
研究概览
简要总结
This study aims to investigate the immediate effects of thoracic mobilization techniques on cough capacity, dyspnea, and pulmonary function in patients with restrictive lung disease. The intervention will be applied in a single session, and outcomes will be measured before and after the intervention to evaluate short-term physiological changes.
详细描述
Restrictive lung disease (RLD) is characterized by reduced lung compliance and limited thoracic mobility, leading to decreased lung volume and impaired respiratory function. Manual therapy interventions such as thoracic mobilization have been proposed to improve chest wall flexibility and enhance respiratory efficiency. However, few studies have examined the immediate clinical effects of such interventions in RLD patients.
This single-group pre-post interventional study will evaluate the short-term outcomes of thoracic mobilization techniques on cough capacity (as measured by peak cough flow), dyspnea (via Borg scale), and pulmonary function (forced vital capacity [FVC], forced expiratory volume in 1 second [FEV1]). The results are expected to provide preliminary evidence on the effectiveness of thoracic mobilization for improving respiratory performance in individuals with RLD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessors will be blinded to group assignment to minimize detection bias during post-intervention evaluations
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 19 years or older
- •Currently receiving respiratory therapy at C Hospital in Sejong City
- •Pulmonary function test indicating restrictive pattern: FVC < 80% and FEV1/FVC ≥ 70%
- •FVC above the lower limit of normal (LLN) for age and sex
- •Diagnosed with restrictive lung disease, such as idiopathic pulmonary fibrosis, scoliosis, or neuromuscular disorders (e.g., myopathy, amyotrophic lateral sclerosis)
排除标准
- •FEV1/FVC ratio < 70%
- •Evidence of airway obstruction on pulmonary function testing
研究组 & 干预措施
conventional therapy group
Participants receive conventional respiratory therapy
干预措施: conventional therapy (Other)
Thoracic mobilization group
Participants receive thoracic mobilization techniques
干预措施: Thoracic mobilization (Other)
Thoracic mobilization group
Participants receive thoracic mobilization techniques
干预措施: conventional therapy (Other)
结局指标
主要结局
Pulmonary function test
时间窗: Immediately before and immediately after intervention on Day 1
Pulmonary function will be assessed using a standard spirometry test, including FVC and FEV1. The test will be conducted by a trained technician according to ATS/ERS guidelines to evaluate respiratory function.
次要结局
- Dyspnea(Immediately before and immediately after intervention on Day 1)
- Cough peak flow(Immediately before and immediately after intervention on Day 1)