TCTR20230330010已完成2 期
An open-label randomized controlled trial of curcumin versus standard dose of omeprazole in treatment of gastroesophageal reflux disease
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 62
研究概览
简要总结
Curcumin 2000 mg daily can significantly improves GERD symptoms and frequency significantly without worsening GERD symptoms. However, comparing these 2 parameters between curcumin and standard omeprazole treatment does not shows statistically significant difference.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 Years 至 65 Years（—）
- 性别
- All
入选标准
- •patients who were diagnosed with gastroesophageal reflux disease (GERD) according to the Thailand GERD guideline 2020
排除标准
- •1 patients presenting with alarm features such as dysphagia, gastrointestinal bleeding, anemia, involuntary weight loss, recurrent vomiting and odynophagia
- •2 pregnant women or women who planned to become pregnant during the study
- •3 patients previously diagnosed with esophageal stricture, esophageal cancer, irritable bowel diseases, hepatobiliary tract obstruction, refractory GERD
- •4 allergy to omeprazole or curcumin
- •5 unable to read and write in Thai language
研究者
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