ACTRN12621000240842已完成2 期
Comparing Oral and Sublingual Ketamine Lozenges as Rescue Analgesics in Adults with Acute pain
niversity of Western Australia0 个研究点目标入组 30 人开始时间: 2021年3月8日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
Ketamine given sublingually and orally produced similar analgesic effects. Sublingual ketamine has faster onset of action and possibly higher rate of adverse effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1) 18years old or above
- •2) Inpatients with acute breakthrough pain of 5 or more on numerical rating scale who required additional medication and previously responded to sublingual ketamine.
- •3) able to self-assess pain scores on NRS
排除标准
- •Patients with known contraindications to ketamine such as: allergy to ketamine; severe cardiovascular disease; history of stroke or cerebral trauma; significant liver disease.
- •Pregnant women or breastfeeding mothers.
研究者
相似试验
已完成
2 期
Topical Ketamine Analgesia in Children Undergoing Tonsillectomy: a Clinical and Serum Level Assays Study.Postoperative PainNCT02720406Assiut University100
已完成
1 期
Ketamine for Cancer PaiAdvanced CancerModerate to Severe PainInadequate analgesiaCancer - Any cancerAnaesthesiology - Pain managementACTRN12621000328875Chris O'brien Lifehouse29
已完成
3 期
Comparison the Effect of Oral Ketamine and Its Peritonsillar Injection in Pain Relief and the Related Phenomenon after a Tonsillectomy OperatioTonsillectomy.Acute tonsillitis, unspecifiedIRCT138811192080N2Arak University of Medical Siences92
已完成
2 期
Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck CancerMucositisHead and Neck CancerNCT01653327Dartmouth-Hitchcock Medical Center11
招募中
2 期
Comparison of oral ketamine and promethazine effect as anesthetic premedication on preoperative anxiety of children ages 3 to 8 yearsIRCT20200921048789N1Islamic Azad University60