跳至主要内容
临床试验/CTRI/2021/05/033503
CTRI/2021/05/033503尚未招募不适用

Clinical profile and outcome in children with Acute Encephalitis Syndrome (AES) -a prospective study

NA1 个研究点 分布在 1 个国家目标入组 154 人开始时间: 2021年12月5日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
NA
入组人数
154
试验地点
1
主要终点
1.Vision

研究概览

简要总结

Acute Encephalitis syndrome (AES ) posses a great public  in India  occurring both epidemics and sporadically .Although JE was know to be main cause of AES in  India and was often paralleled with AES, studies conducted shows  a shift in perception of etiology of AES in INDIA  which is vey wide and often the cause reminds unknown . This is prospective observational  study to be conducted in Kasturba Hospital ,Manipal.All cases admitted with symptoms suggestive of AES will be included in the study after application of inclusion and exclusion criteria .Detailed clinical examination and investigations done as a part of standard care will be documented, entered  in predetermined proforma .Details of treatment and hospital course will be included and outcome will be measured at the discharge and at 3 month follow up.

研究设计

研究类型
Observational

入排标准

年龄范围
1.00 Month(s) 至 18.00 Year(s)(—)
性别
All

入选标准

  • All children 1 month to 18 yrs old diagnosed with Acute Encephalitis Syndrome in Kasturba hospital,Manipal.

排除标准

  • Toxic Encephalopathy 2.Hypertensive Encephalopathy 3.Major congenital anamoliespredisposing to infection .Eg Spina bifida,Meningocele,CSF Rhinorrhoea 4.History of head injury 5Inborn Errors of metabolism.

结局指标

主要结局

1.Vision

时间窗: Outcome assessed at discharge and at first follow up in 3 months

2.Hearing

时间窗: Outcome assessed at discharge and at first follow up in 3 months

5.Neurodeficits

时间窗: Outcome assessed at discharge and at first follow up in 3 months

4.Glasgow coma scale

时间窗: Outcome assessed at discharge and at first follow up in 3 months

3.Seizures

时间窗: Outcome assessed at discharge and at first follow up in 3 months

6.Discharged /Death

时间窗: Outcome assessed at discharge and at first follow up in 3 months

次要结局

未报告次要终点

研究者

发起方
NA
申办方类型
Other [na]

研究点 (1)

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