PACTR202105618971235已完成2 期
Clinical validation of a CYP2B6 pharmacogenetics test and dosing algorithm in the safe and efficacious use of Efavirenz and its cost effective & benefit analysis in a public healthcare setting
未提供0 个研究点目标入组 260 人开始时间: 2021年4月27日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 260
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 19 Year(s) 至 44 Year(s)（—）
- 性别
- All
入选标准
- •1. HIV infected adults between 18 and 50 years
- •2. CD4 T-cell counts between 50-500 cells per ul
- •3. No previous AIDS defining illness
- •4. Plasma HIV-1 RNA of at least 1000 copies per ml
- •5. No short course for preventing mother to child transmission
- •6. No previous exposure to antiretroviral therapy
排除标准
- •1. Pregnancy or nursing mothers
- •2. Had uncontrolled active opportunistic or malignant disease
- •3. Present or recent use of prohibited or elicit medications adversely affecting participation
- •4. Laboratory values outside predefined ranges -
- •i. Absolute neutrophil count <500 celss per ul
- •ii. Haemoglobin <7.0 g/dl
- •iii. Platelet count <50 000 cells per ul
- •iv. Aspartate aminotransferase, or alanine aminotransferase, or both >5 times the upper limit normal
研究者
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