To Assess the Safety and Efficacy of Two Subthreshold Parameters (5% and 15% Duty Cycle (DC)) Compared to Standard ETDRS (Early Treatment of Diabetic Retinopathy Study) Continuous Wave (CW) Laser
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 主要终点
- 1. Decrease in number of leaking Mas on FFA 2. Decrease in diffuse leakage on FFA
研究概览
简要总结
To assess the safety and efficacy of two subthreshold parameters (5% and 15% duty cycle (DC)) compared to standard ETDRS (early treatment of diabetic retinopathy study) continuous wave (CW) laser
详细描述
Test burn up to barely visible burn with micropulse laser, then reduce the power by 70% and perform laser with various DC (5%, 15%, cw) as per the group.
Focal to Mas+ confluent burns to areas of diffuse leakage
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Eyes with DME (center or non-center involving) with <350 microns central retinal thickness
排除标准
- •Subfoveal exudates, history of VR surgery, history of macular laser
结局指标
主要结局
1. Decrease in number of leaking Mas on FFA 2. Decrease in diffuse leakage on FFA
时间窗: 3 months
Comparing the number of leaking microaneuyrms baseline to 6 weeks with 3 types of lasers (two subthreshold parameters (5% and 15% duty cycle (DC)) compared to standard ETDRS continuous wave (CW) laser.
次要结局
未报告次要终点
研究者
Dr Jay Chhablani
Principal Investigator
L.V. Prasad Eye Institute