Trauma-focused CBT vs. EMDR in the Treatment of Posttraumatic Stress Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- PTSD symptom severity: (a) interviewer rating (PSS-I); (b) self-report (PDS)
研究概览
简要总结
This study will evaluate the effectiveness of trauma-focused cognitive behaviour therapy (TF-CBT) versus eye movement desensitization and reprocessing (EMDR) in the treatment of trauma survivors with post-traumatic stress disorder (PTSD). Patients will be randomly assigned to TF-CBT or EMDR. Follow-up assessments will be conducted at 3 and 12 months post-treatment. In addition to comparing the efficacy of the two protocols, an additional focus will lie on identifying predictors for treatment outcome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A full diagnosis of PTSD according to the DSM-IV or subthreshold PTSD (criteria for intrusive re-experiencing are fulfilled and either three avoidance/numbing symptoms or two hyperarousal symptoms are present)
- •PTSD is related to one or more single-event traumas and participants have a clear memory of this event/these events (sufficient for constructing scenes to be used in exposure)
- •Age between 18 and 70
- •Sufficient fluency in Dutch to complete treatment and research protocol
- •If participants are using anti-depressants, they need to be on a stable dose for at least 2 weeks before the beginning of treatment and remain on this dose throughout the treatment.
排除标准
- •Dementia or other severe cognitive impairment
- •Psychosis
- •Depression with suicidal ideation
- •Bipolar disorder
- •Borderline Personality Disorder
- •Anti-social personality disorder
- •Substance dependence
- •Current use of tranquilizers
- •Exposure to prolonged and/or chronic trauma ("type-II-trauma")
研究组 & 干预措施
Treatment group 1
Trauma-focused Cognitive Behavior Therapy (TF-CBT)
干预措施: Trauma-focused Cognitive Behavior Therapy (Behavioral)
Treatment group 2
Eye Movement Desensitization and Reprocessing (EMDR)
干预措施: Eye Movement Desensitization and Reprocessing (EMDR) (Behavioral)
结局指标
主要结局
PTSD symptom severity: (a) interviewer rating (PSS-I); (b) self-report (PDS)
时间窗: Assessed at post-treatment, 3 months and 12 months follow-up
次要结局
- Depressive symptom severity (Beck Depression Inventory, BDI)(assessed at post-treatment, 3 months and 12 months follow-up)
- Severity of anxiety symptoms (Beck Anxiety Inventory, BAI)(assessed at posttreatment, 3 months and 12 months follow-up)
- Trauma-related appraisal (Posttraumatic Cognitions Inventory, PTCI)(post-treatment)
研究者
Paul M.G.Emmelkamp
Professor
VU University of Amsterdam