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临床试验/NCT06958029
NCT06958029招募中不适用

Incidence and Risk Factors of Postoperative Atrial Fibrillation in Cardiac Surgery Patients

Khon Kaen University1 个研究点 分布在 1 个国家目标入组 275 人开始时间: 2025年4月1日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
275
试验地点
1
主要终点
Incidence

研究概览

简要总结

This multicenter observational study aims to investigate the incidence and identify risk factors associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery at three medical centers in Thailand. The study will examine patient characteristics, surgical factors, and anesthetic management practices that may contribute to the development of this common postoperative complication.

详细描述

Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery, with incidence rates reported between 15-30% after valve surgery and 18-74% after coronary artery bypass grafting. POAF typically occurs within 72 hours after surgery and is associated with increased morbidity, mortality, length of hospital stay, and healthcare costs.

The Society of Thoracic Surgeons has identified five major postoperative complications associated with cardiac surgery, including POAF, which can significantly affect patient outcomes. This multicenter observational study will examine the incidence and risk factors of POAF in cardiac surgery patients across three medical centers in Thailand: Srinagarind Hospital at Khon Kaen University, Northeastern Thailand Cardiac Center, and Surat Thani Hospital.

The study will collect data on patient demographics, comorbidities, preoperative laboratory values, perioperative characteristics, surgical procedures (valve surgery, CABG, combined procedures), and postoperative complications. By identifying risk factors associated with POAF, this study aims to develop preventive strategies and improve management protocols for patients at high risk for this complication.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years
  • Patients undergoing cardiac valve surgery or coronary artery bypass grafting (CABG) procedures

排除标准

  • Patients undergoing aortic surgery
  • Patients undergoing MAZE procedure
  • Incomplete medical records
  • Patients who required mechanical circulatory support before surgery
  • Patients who died during surgery or within 3 days after surgery

结局指标

主要结局

Incidence

时间窗: 72 hours postoperatively

The incidence of POAF

次要结局

  • Risk factors(72 hours postoperatively)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Thepakorn Sathitkarnmanee

Associate professor

Khon Kaen University

研究点 (1)

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