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临床试验/NCT03082326
NCT03082326已完成不适用

The Critical Care Ultrasound Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value

West China Hospital1 个研究点 分布在 1 个国家目标入组 181 人开始时间: 2016年4月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
181
试验地点
1
主要终点
all cause mortality

研究概览

简要总结

Shock is a common condition in critical care unit (ICU). It is extremely important that the patient accepts early goal-directed therapy (EGDT) treatment in the early stage of shock. However, several studies failed to demonstrate that the well used variables such as CVP and others could direct to a better treatment. In recent years, critical care ultrasound (CCUS) has been respected as a reliable noninvasive tool and widely used in ICU practice. With CCUS the investigators can accurately acquired the detailed information of the characteristic of the hemodynamics and lung pathology (the systole and diastole function, volume status, valve insufficiency, lung, edema, consolidation, and pleural effusion, etc.). To the investigators knowledge, there is no study investigating the epidemic of such ultrasonic variables and its value to predict to outcome. The aim of this study is to investigate the epidemic and the prognostic value of CCUS Based Characteristic of Hemodynamic and Lung pathology in Early Stage of Shock in patients admitted in ICU.

详细描述

Adult patients who admitted to the intensive care unit of West China hospital of sichuan university with shock from April 2016 to April 2017 enrolled.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • SBP<90 mm Hg or MAP <70 mm Hg or SBP decrease >40mmHg or need vasoactive drugs;
  • Skin that is cold and clammy, capillary refill time >4.5s, urine output of <0.5ml/Kg.hr and lactate>2mmol/L;
  • SHOCK presented within 6 hr.

排除标准

  • <18 years old;
  • Patient or family member refuse to be enrolled.

结局指标

主要结局

all cause mortality

时间窗: 28 days

次要结局

  • ICU length of stay(through study completion, an average of 28 days)
  • length of mechanical ventilation(through study completion, an average of 28 days)
  • hospital length of stay(through study completion, an average of 28 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

tongjuan ZOU

Doctor

West China Hospital

研究点 (1)

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