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临床试验/NCT02219425
NCT02219425已完成不适用

Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women

University of Aarhus1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2014年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Gene Expression of the Endometrium after an endometrial biopsy

研究概览

简要总结

The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.

详细描述

An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7.

Tissue is analysed and compared for changes in gene expression profile using Seq RNA

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Fertile women
  • Age: 18-40 years
  • BMI: 18-32
  • Regular menstrual cycle
  • No use of hormonal contraceptives or IUD the last 3 months

排除标准

  • Patients in need of a interpreter
  • Suspected intrauterine abnormalities
  • Pregnancy

结局指标

主要结局

Gene Expression of the Endometrium after an endometrial biopsy

时间窗: 1 month between each biopsy

An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7. Endometrial tissue is analysed for changes in gene expression profile of various chemokines and cytokines using RNA Sequencing technology

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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