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临床试验/NCT04157530
NCT04157530已完成不适用

Clinical Evaluation of Acupuncture in Treating Glaucoma

China Medical University Hospital2 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2018年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
45
试验地点
2
主要终点
intraocular pressure

研究概览

简要总结

The present study predicts that acupuncture or electroacupuncture can reduce intraocular pressure and also can improve quality of life in patients with glaucoma.

详细描述

Glaucoma is a syndrome, and that is results from intraocular pressure increases cause visual field narrow and blindness. The incidence of adult blindness induced by glaucoma is second in the ophthalmologic disease in the world. Many studies report that both blood circulation in the eye surroundings and intraocular pressure increase play an important role in glaucoma. Several studies show that acupuncture can modulate intraocular pressure and improve activity of central visual acuity and also increase blood flow of eye fundus. Jingming (BL1) can communicate yi and yang, and nourish and clear eyes, Qiuhou (EX-HN7) can transport qi and activate blood, and freely flowing meridian and clear eyes. Therefore, the purpose of the present study was to investigate the therapeutic effect of acupuncture at Jinming and Qiuhou on intraocular pressure in patients with glaucoma. The study designed as a single-blinded, randomized, controlled clinical trial, a total of45 patients with glaucoma divided into three groups, each group was15 subjects as follows: 1) sham group, using the seeds of wang-bu-liu-xing applied on the surface of Jinming and Qiuhou acupoints, one times/day, and each time was 20 min, twice/week for 2 weeks; 2) acupuncture group, the methods were identical to the sham group, but used acupuncture applied to Qingming and Qiuhou with Der-qi; 3) Electroacupuncture group, the methods were identical to acupuncture, but the needles of Qinming and Qiuhou connected to the electroacupuncture machine after Der-qi, the frequencies of stimulus were 6 Hz, the intensity of stimulus was minimal visible muscle twitch. Primary outcome measure was the changes of intraocular pressure, and the second outcome measure was the score changes of WHOQOL-REF (Taiwan version).

The present study predicts that acupuncture or electroacupuncture can reduce intraocular pressure and also can improve quality of life in patients with glaucoma.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Glaucoma for at least three months
  • Do not use ocular hypotensive drugs or use only one ocular hypotensive drug.
  • It is over 20 years old.
  • Men and women are informal.
  • There is no evidence other than glaucoma that shows other eye diseases.
  • Be aware and fill out the consent form yourself.

排除标准

  • Combines other chronic diseases, taking multiple medications such as high blood pressure, diabetes, etc.
  • Those who have had glaucoma surgery.
  • Those who had undergone myopia laser surgery.
  • Can not accept acupuncture points stimulators.
  • Allergic to acupuncture needles.
  • Has a mental illness or is unable to cooperate with the researcher.
  • Do not sign consent

结局指标

主要结局

intraocular pressure

时间窗: 20 min, twice/week for 2 weeks

Primary outcome measure was the changes of intraocular pressure,

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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