Definition of Respiratory Training Protocols in Obese Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- V'O2 peak during physical exercise protocol
研究概览
简要总结
The project is aimed at investigating the effectiveness of respiratory training protocols in relieving exercise dyspnea, improving respiratory efficiency and the ability to perform physical activity, even daily, in obese patients.
Therefore, some respiratory exercises with different characteristics and mechanisms of action will be introduced into the standard program of integrated metabolic rehabilitation implemented at the Istituto Auxologico Italiano, Piancavallo, Italy (Division of Auxology and Division of Metabolic Diseases) in order to identify a suitable training protocol for this population, the development of which can be carried out over time by patients even autonomously (Sheel and Dominelli 2019). The definition of the protocols will be based on what has been observed by recent studies conducted on healthy people (Wuthrich et al., 2015; Schaer et al., 2018) and on patient populations in which respiratory dysfunction is a primary or secondary component of the pathology (Calcaterra et al., 2014; Pomidori et al., 2009). All planned interventions are safe and will be adapted to the obese patient.
详细描述
Project objectives are:
- evaluation of acute physiological responses, before and immediately after the single training session of the respiratory muscles conducted in the first days of hospitalization of the patients in the clinic.
- evaluation of physiological responses chronically, at the beginning and at the end of the three weeks of each workout The ultimate goal of this project will be to introduce targeted exercises for the respiratory muscles among the intervention guidelines for the prevention and reduction of obesity, especially juvenile, in order to break the vicious circle that is created in these patients, inactivity-obesity-inactivity, to create greater awareness of the body and the importance of a more active and healthy lifestyle and finally to have a greater consolidated effectiveness of intervention.
Materials and methods:
Subjects The study will be attended by 20 obese boys/young adults aged between 14 and 30 years old recruited at the Division of Auxology and the Division of Metabolic Diseases, Istitutio Auxologico Italiano, Piancavallo (VB).
Criteria for inclusion in the study group are:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 30 Years（Child, Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •BMI standard deviation score (SDS) > 2 for patients aged < 18 years and BMI > 35 for patients aged > 18 years;
- •absence of structured physical activity programs (regular activity for more than 120 min/week) during the 6 months preceding the study;
- •absence of signs/symptoms referable to cardiovascular, respiratory, gastrointestinal, or musculoskeletal pathologies contraindicated for carrying out the tests.
排除标准
- •presence of structured physical activity programs (regular activity for more than 120 min/week) during the 6 months preceding the study;
- •presence of signs/symptoms referable to cardiovascular, respiratory, gastrointestinal, or musculoskeletal pathologies contraindicated for carrying out the tests.
结局指标
主要结局
V'O2 peak during physical exercise protocol
时间窗: Baseline and at the end of the training program (21 days)
Change in V'O2 peak
Arterial saturation of O2 during physical exercise protocol
时间窗: Baseline and at the end of the training program (21 days)
Change in arterial saturation of O2
次要结局
- Heart rate during physical exercise protocol(Baseline and at the end of the training program (21 days))