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临床试验/NCT06128057
NCT06128057尚未招募不适用

Comparing Trauma Associated Severe Hemorrhage "TASH" Score and Modified Traumatic Bleeding Severity Score "MTBSS" in Trauma Patients in Need for Massive Blood Transfusion in Assiut University Hospital

Assiut University0 个研究点目标入组 140 人开始时间: 2023年12月5日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
140
主要终点
Compare predictive value of TASH Score And MTBBS In need for Massive Blood Transfusion

研究概览

简要总结

Evaluate And Compare predictive value of TASH Score And MTBBS In need for Massive Blood Transfusion

详细描述

Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.Despite improvements in trauma systems worldwide, trauma continues to be one of the leading causes of death and disability in all age groups, especially the young and middle age group.

Approximately 5.8 million people die each year due to trauma related injuries, representing 8% of the worldwide mortality Polytrauma is a short verbal equivalent commonly used for severely injured patients usually with associated injury (i.e. two or more severe injuries in at least two different areas of the body), less often with a multiple injury (i.e. two or more severe injuries in one body area). Polytrauma patients usually have a much higher risk of mortalities and disabilities than the risk of expected mortalities in individual injuries patients.

Even though polytrauma can occur due to different causes such as road traffic accidents, fall from heights bullet injuries, suicide and homicide

.Yet the leading cause of traumatic related causes of death worldwide is road traffic accidents Egypt, in particular, has experienced an alarming increase in the burden of traumatic injuries. According to the World Health Organization In 2015 Egypt has one of the highest rates of road accidents worldwide, with more than 12,000 fatalities each year, one of the highest among Eastern Mediterranean countries. Although 90% of world's road trauma related fatalities occur in low- and middle-income countries, Injury

prevention and trauma care programs in these countries have remained deficient. The prediction of ongoing hemorrhage in severe trauma patients is challenging, and 14 scoring systems or algorithms have been developed to guide clinicians in this critical situation , the early identification of trauma patients with ongoing hemorrhage is pivotal for addressing their critical condition. Many of the scores are used in daily clinical practice and seem to be an interesting tool in the management of massive bleeding. The best scoring system would probably be one that combines superior accuracy in predicting the need for MT with an ease of use that would allow early identification of patients requiring Massive blood trasfusion.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients aged more than 18 years on both gender

排除标准

  • patients below 18 years
  • patients with known bleeding disorders such as hemophilia or von Willebrand disease
  • non trauma related bleeding : patients with severe hemorrhage unrelated to traumatic injury such as GI bleeding and ruptured aneurysm
  • transfer from other facilities if their initial trauma records and scoring data are not available

结局指标

主要结局

Compare predictive value of TASH Score And MTBBS In need for Massive Blood Transfusion

时间窗: Baseline

Comparing odd number ( TASH score ) with even number (MTBSS ) in prediction for need for massive blood transfusion

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Abdelrhman Abouzeid

Resident

Assiut University

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